R-PLEX Human sFas Antibody Set

R-PLEX Human sFas Antibody Set Overview
The R-PLEX Human sFas Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of sFas in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human sFas Antibody Set Features
  • Measures human sFas in serum, plasma, and urine
  • Dynamic range: 4.3 - 5,000 pg/mL
  • Median LLOD: 4.3 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human sFas Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human sFas Antibody Set Calibration Curve
Calibration curve for R-PLEX Human sFas Antibody Set
sFas Analyte

Description - sFas (APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, FAS) is a 48 kDa, type I membrane protein that plays a critical role in apoptosis. Soluble Fas (sFas) is at least in part the result of alternative splicing, and competitively inhibits binding of FasL to Fas receptors. This reduces Fas-induced signaling, including apoptosis. sFas is present in activated human lymphocytes and tumor cell lines supernatants. Elevated levels have been observed in patients suffering from systemic lupus.

Disease Research Area - Lupus

Application Area - Apoptosis

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5 plate size
50 plate size
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