R-PLEX Human PYY (total) Antibody Set

Please note: This analyte is also sold as a U-PLEX assay. Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.

R-PLEX Human PYY (total) Overview
The R-PLEX Human PYY (total) includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of PYY (total) in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human PYY (total) Features
  • Measures human PYY (total) in Serum, Plasma
  • Dynamic range: 1.4 - 3,000 pg/mL
  • Median LLOD: 1.4 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human PYY (total) was assessed and representative data is presented below.

Figure 1. R-PLEX Human PYY (total) Calibration Curve
Calibration curve for R-PLEX Human PYY (total)
PYY (total) Analyte

Description - Peptide YY (PYY, PYY-I, PYY1) is secreted from the intestinal L cells in proportion to the caloric content of a meal. Plasma PYY levels rise within 15 minutes after starting to eat and plateau within approximately 90 minutes. Two forms, PYY(1-36) and PYY(3-36) are released into circulation. PYY acts on neuropeptide Y (NPY) receptors in the CNS to mediate satiety. Administration of PYY(3-36) reduces energy intake and body weight in both humans and animals.This antibody set recognizes human PYY (total). Samples from other species were not tested.

Application Area - Metabolic Disease

  • Recommended Components
  • Specifications
  • Kit Contents
  • References
  • Documentation
Customer Service/Orders

Scientific/Technical Support

Instrument Support

Company Headquarters