Please note: This analyte is also sold as a U-PLEX assay.
Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.
R-PLEX Human PYY (total) Overview The R-PLEX Human PYY (total) includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of PYY (total) in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
click here.
R-PLEX Human PYY (total) Features - Measures human PYY (total) in Serum, Plasma
- Dynamic range: 1.4 - 3,000 pg/mL
- Median LLOD: 1.4 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data Calibration curve for the R-PLEX Human PYY (total) was assessed and representative data is presented below.
Figure 1. R-PLEX Human PYY (total) Calibration Curve PYY (total) Analyte
Description - Peptide YY (PYY, PYY-I, PYY1) is secreted from the intestinal L cells in proportion to the caloric content of a meal. Plasma PYY levels rise within 15 minutes after starting to eat and plateau within approximately 90 minutes. Two forms, PYY(1-36) and PYY(3-36) are released into circulation. PYY acts on neuropeptide Y (NPY) receptors in the CNS to mediate satiety. Administration of PYY(3-36) reduces energy intake and body weight in both humans and animals.This antibody set recognizes human PYY (total). Samples from other species were not tested.
Application Area - Metabolic Disease
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Recommended Components
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Specifications
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Documentation
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References
Why do I need other components
Catalog No.
Product Name
Size
R50AA-4
R60AM-1
L45SA-1
Application(s)
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Metabolic
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Analyte(s)
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PYY (total)
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Species
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Human
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Rabbit Polyclonal
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LLOD (Sensitivity)
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1.40 pg/mL
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Dynamic Range
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1.40-3000 pg/mL
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Sample Type
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Serum, Plasma
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Recombinant standards
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Recombinant
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID(s)
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5697
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UniProt ID(s)
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P10082
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Assay Diluent(s)
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Diluent 43
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Antibody Diluent(s)
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Diluent 3
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Product Inserts
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Datasheets
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Handouts
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SDS
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Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters