R-PLEX Human Osteoactivin Antibody Set

R-PLEX Human Osteoactivin Antibody Set Overview
The R-PLEX Human Osteoactivin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Osteoactivin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human Osteoactivin Antibody Set Features
  • Measures human Osteoactivin in serum, plasma, and urine
  • Dynamic range: 12 - 40,000 pg/mL
  • Median LLOD: 12 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human Osteoactivin Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human Osteoactivin Antibody Set Calibration Curve
Calibration curve for R-PLEX Human Osteoactivin Antibody Set
Osteoactivin Analyte

Description - Osteoactivin (OA, GPNMB, HGFIN, NMB, glycoprotein nmb) is a transmembrane glycoprotein expressed in various cell types, including melanocytes, osteoclasts, macrophages, dendritic cells, and tumor cells. High levels of osteoactivin expression in normal and inflammatory kidney and liver macrophages suggest its significant role in acute injury in these organs. Upregulation of osteoactivin in the tubular epithelium in response to renal injury has been implicated in the triggering of renal interstitial fibrosis.

Disease Research Area - Renal And Hepatic Fibrosis

Application Area - Oncology & Cancer

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5 plate size
50 plate size
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