R-PLEX Human Leptin Antibody Set

Please note: This analyte is also sold as a U-PLEX assay. Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.

R-PLEX Human Leptin Antibody Set Overview
The R-PLEX Human Leptin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Leptin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human Leptin Antibody Set Features
  • Measures human Leptin in serum and plasma
  • Dynamic range: 80-400,000 pg/mL
  • Median LLOD: 80 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human Leptin Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human Leptin Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human Leptin Antibody Set
Leptin Analyte

Description - Leptin (OB, OBS, LEP, LEPD) is released by adipocytes. Leptin plays a key role in metabolism and regulation of adipose tissue. It is released in amounts mirroring overall body fat stores and acts on neurons and hypothalamic receptors, thereby influencing the brain’s perception of appetite. The absence of leptin leads to uncontrolled food intake and resulting obesity. Leptin may be a critical regulator of obesity that is often accompanied by insulin resistance and hyperinsulinemia.

Disease Research Area - Metabolic Diseases

Application Area - Metabolic

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