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The R-PLEX platform offers both antibody sets and assays for a wide menu of biomarkers. The R-PLEX Human IRS-1 Assay has the essential components to build an assay that measures IRS-1 in a single analyte format. For information on multiplexing IRS-1 with other analytes, please see the
R-PLEX Assay Designer or the
R-PLEX Human IRS-1 Antibody Set.
The Product Insert for R-PLEX Assays provides detailed instructions for building a singleplex assay. The datasheet for IRS-1 provides information on the components (including calibrator stock concentration), recommended sample types and dilution factors, and representative data for analytical performance. These items and other helpful documents can be found in the "Documentation" tab below.
Related Key TermsMetabolic Diseases, Insulin Receptor Substrate 1, IRS-1
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Specifications
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Kit Contents
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Documentation
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References
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Application(s)
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Metabolic
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Analyte(s)
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IRS-1
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Species
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Human
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Instrument(s)
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SECTOR Imager 2400
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SECTOR Imager 6000
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MESO QuickPlex SQ 120
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MESO QuickPlex SQ 120MM
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MESO SECTOR S 600
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MESO SECTOR S 600MM
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Plate Type
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96-well
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LLOD (Sensitivity)
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63 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Gene ID(s)
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3667
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UniProt ID(s)
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P35568
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Schedule B Code
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3822.19.0000
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Product Description
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Storage
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Quantity per Kit
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Human IRS-1 Antibody Set
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2-8 °C
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1 each
(5 plate size)
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Human IRS-1 Calibrator
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≤-70 °C
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5 vial
(1 vial)
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2-8 °C
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5 each
(1 plate)
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2-8 °C
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1 bottle
(50 mL)
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≤-10 °C
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1 bottle
(50 mL)
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≤-10 °C
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1 bottle
(50 mL)
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RT
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1 bottle
(90 mL)
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Product Inserts
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Datasheets
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Handouts
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SDS
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Title
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Journal
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Year
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Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition.
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Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase.
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Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth.
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Efficacy of Ganitumab (AMG 479), Alone and in Combination With Rapamycin, in Ewing's and Osteogenic Sarcoma Models.
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Chronic treatment with epoxyeicosatrienoic acids modulates insulin signaling and prevents insulin resistance in hepatocytes.
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View All
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