Please note: This analyte is also sold as a U-PLEX assay.
Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.
R-PLEX Insulin Antibody Set Overview The R-PLEX Insulin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Insulin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
click here.
R-PLEX Insulin Antibody Set Features - Measures Insulin in serum and plasma
- Dynamic range: 17-50,000 pg/mL
- Median LLOD: 17 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data Calibration curve for the R-PLEX Insulin Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Insulin Antibody Set Calibration Curve Insulin Analyte
Description - Insulin is a peptide hormone that is produced in the pancreas by β cells. Insulin is involved in the regulation of carbohydrate, fat, and protein metabolism. Low levels of insulin cause liver cells to convert glycogen to glucose and secrete it into the blood. Type 1 diabetes results when the β cells no longer produce insulin resulting in high glucose levels. Individuals with type 1 diabetes depend on exogenous insulin for their survival because of an absolute deficiency of the hormone.
Disease Research Area - Metabolic Diseases
Application Area - Metabolic
-
Recommended Components
-
Specifications
-
-
Documentation
-
References
Why do I need other components
Catalog No.
Product Name
Size
R50JA-4
R50AA-4
R60AM-1
L45SA-1
Application(s)
|
|
Metabolic
|
|
Analyte(s)
|
|
Insulin
|
|
Species
|
|
Human
|
|
Capture Antibody
|
|
Mouse Monoclonal
|
|
Detection Antibody
|
|
Mouse Monoclonal
|
|
LLOD (Sensitivity)
|
|
17 pg/mL
|
|
Dynamic Range
|
|
17-50,000 pg/mL
|
|
Sample Type
|
|
Serum, Plasma
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
Storage Statement(s)
|
|
Please refer to the product insert for the storage conditions of individual kit components.
|
|
Storage Condition
|
|
Multi-Component
|
|
Gene ID(s)
|
|
3630
|
|
UniProt ID(s)
|
|
P01308
|
|
Assay Diluent(s)
|
|
Diluent 13
|
|
Antibody Diluent(s)
|
|
Diluent 12
|
|
Product Inserts
|
|
|
Datasheets
|
|
|
Handouts
|
|
|
SDS
|
|
|
Title
|
Journal
|
Year
|
|
Islet Autoantibody Standardization Program: interlaboratory comparison of insulin autoantibody assay performance in 2018 and 2020 workshops
|
|
|
|
Leptin levels are associated with multiple sclerosis risk
|
|
|
|
Effect of orally administered L. fermentum NCIMB 5221 on markers of metabolic syndrome: an in vivo analysis using ZDF rats
|
|
|
|
Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo.
|
|
|
|
Fibroblast growth factor 21 mediates specific glucagon actions.
|
|
|
|
View All
|
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters