R-PLEX Human GIP Total Antibody Set

Please note: This analyte is also sold as a U-PLEX assay. Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.

R-PLEX Human GIP (total) Antibody Set Overview
The R-PLEX Human GIP (total) Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of GIP (total) in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human GIP (total) Antibody Set Features
  • Measures human GIP (total) in serum and plasma
  • Dynamic range: 4.8 - 6,500 pg/mL
  • Median LLOD: 4.8 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human GIP (total) Antibody Set was assessed and representative data are presented below

Figure 1. R-PLEX Human GIP (total) Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human GIP Total Antibody Set

GIP (total) Analyte

Description - Gastric Inhibitory Polypeptide (GIP, Glucose-dependent Insulinotropic Polypeptide, incretin) is synthesized by enteroendocrine K cells and is secreted into plasma in response to nutrient flow. GIP binds to G-protein coupled receptors in many tissues. GIP protects the small intestine from acid damage and induces insulin secretion. It has been reported that Type 2 diabetics are resistant to GIP. The GIP (total) assay recognizes both the active (1-42) and inactive (3-42) forms of GIP.

Disease Research Area - Metabolic Diseases

Application Area - Metabolic

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