Please note: This analyte is also sold as a U-PLEX assay.
Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.
R-PLEX Human GIP (total) Antibody Set Overview The R-PLEX Human GIP (total) Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of GIP (total) in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
click here.
R-PLEX Human GIP (total) Antibody Set Features - Measures human GIP (total) in serum and plasma
- Dynamic range: 4.8 - 6,500 pg/mL
- Median LLOD: 4.8 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data Calibration curve for the R-PLEX Human GIP (total) Antibody Set was assessed and representative data are presented below
Figure 1. R-PLEX Human GIP (total) Antibody Set Calibration Curve
GIP (total) Analyte
Description - Gastric Inhibitory Polypeptide (GIP, Glucose-dependent Insulinotropic Polypeptide, incretin) is synthesized by enteroendocrine K cells and is secreted into plasma in response to nutrient flow. GIP binds to G-protein coupled receptors in many tissues. GIP protects the small intestine from acid damage and induces insulin secretion. It has been reported that Type 2 diabetics are resistant to GIP. The GIP (total) assay recognizes both the active (1-42) and inactive (3-42) forms of GIP.
Disease Research Area - Metabolic Diseases
Application Area - Metabolic
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Recommended Components
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Specifications
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Documentation
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References
Why do I need other components
Catalog No.
Product Name
Size
R50JA-4
R50AA-4
R60AM-1
L45SA-1
Application(s)
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Metabolic
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Analyte(s)
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GIP (total)
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Species
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Human
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Mouse Monoclonal
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LLOD (Sensitivity)
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4.8 pg/mL
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Dynamic Range
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4.8 - 6,500 pg/mL
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Sample Type
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Serum, Plasma
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID(s)
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2695
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UniProt ID(s)
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P09681
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Assay Diluent(s)
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Diluent 13
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Antibody Diluent(s)
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Diluent 12
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Product Inserts
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Datasheets
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Handouts
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SDS
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Title
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Journal
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Year
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Impact of intestinal electrical stimulation on nutrient-induced GLP-1 secretion in vivo.
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Roux-en-Y gastric bypass surgery but not vertical sleeve gastrectomy decreases bone mass in male rats.
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