R-PLEX Human FasL Antibody Set

R-PLEX Human FasL Antibody Set Overview
The R-PLEX Human FasL Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of FasL in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human FasL Antibody Set Features
  • Measures human FasL in serum, plasma, and urine
  • Dynamic range: 1.1 - 2,500 pg/mL
  • Median LLOD: 1.1 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human FasL Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human FasL Antibody Set Calibration Curve
Calibration curve for R-PLEX Human FasL Antibody Set
FasL Analyte

Description - Fas ligand (FasL, APTL, CD178, CD95L, ALPS1B, CD95-L, TNFSF6, TNLG1A, APT1LG1, FASLG, CD95L) is a homotrimeric, type II membrane protein that belongs to the tumor necrosis factor family (TNF). FasL induces apoptosis in Fas (CD95/APO-1)-expressing cells. FasL surface expression is regulated by post-translational shedding at an MMP-7 cleavage site, resulting in the release of soluble FasL into serum. FasL deficiencies have been implicated in tumor drug resistance, oncogenesis, and autoimmune disorders.

Disease Research Area - Cancer, Autoimmune Disorders

Application Area - Apoptosis, Immunology

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5 plate size
50 plate size
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