R-PLEX Human BAFF Antibody Set

Please note: This analyte is also sold as a U-PLEX assay. Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.

R-PLEX Human BAFF Antibody Set Overview
The R-PLEX Human BAFF Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of BAFF in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human BAFF Antibody Set Features
  • Measures human BAFF in serum and plasma
  • Dynamic range: 0.16-1,900 pg/mL
  • Median LLOD: 0.16 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human BAFF Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human BAFF Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human BAFF Antibody Set
BAFF Analyte

Description - B-cell Activating Factor (BAFF, TNFSF13B, BLyS, CD257) binds to its cognate receptor BAFF-R, and to both TNFRSF13B (TACI) and TNFRSF17 (BCMA). BAFF is a poten B-cell activator and is important in their proliferation and differentiation. Insufficient levels lead to immunodeficiency. Excessive levels can result in autoimmune disorders, so BAFF is a target for antibody therapy. BAFF may also be considered a metabokine because of its linkage between metabolic disorders and the immune system.

Disease Research Area - Autoimmune & Inflammation

Application Area - Immunogenicity, Metabolic

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