Please note: This analyte is also sold as a U-PLEX assay.
Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.
R-PLEX Glucagon Antibody Set Overview The R-PLEX Glucagon Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Glucagon in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
click here.
R-PLEX Glucagon Antibody Set Features - Measures Glucagon in serum and plasma
- Dynamic range: 0.08-400 pg/mL
- Median LLOD: 0.08 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data Calibration curve for the R-PLEX Glucagon Antibody Set was assessed and representative data are presented below.
Figure 1. R-PLEX Glucagon Antibody Set Calibration Curve Glucagon Analyte
Description - Glucagon (GCG) is a polypeptide hormone that is produced by the α-cells in the pancreas. Glucagon is involved in maintaining normal levels of glucose in the blood by causing the liver to convert glycogen into glucose. It stimulates hepatic glycogenolysis, gluconeogenesis, and ketogenesis, which are antagonistic effects to those of insulin action, resulting in increased blood glucose levels. Glucagon receptors are present in liver, kidney, intestinal smooth muscle, brain, and adipose tissue.
Disease Research Area - Metabolic Diseases
Application Area - Metabolic
-
Recommended Components
-
Specifications
-
-
Documentation
-
References
Why do I need other components
Catalog No.
Product Name
Size
R50JA-4
R50JA-4
R60AM-1
L45SA-1
Application(s)
|
|
Metabolic
|
|
Analyte(s)
|
|
Glucagon
|
|
Species
|
|
Non-human primate, Mouse, Rat
|
|
Capture Antibody
|
|
Mouse Monoclonal
|
|
Detection Antibody
|
|
Mouse Monoclonal
|
|
LLOD (Sensitivity)
|
|
0.08 pg/mL
|
|
Dynamic Range
|
|
0.08-400 pg/mL
|
|
Sample Type
|
|
Serum, Plasma
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
Storage Condition
|
|
Multi-Component
|
|
Gene ID(s)
|
|
14526, 24952
|
|
UniProt ID(s)
|
|
P55095, P06883
|
|
Assay Diluent(s)
|
|
Diluent 12
|
|
Antibody Diluent(s)
|
|
Diluent 11
|
|
Product Inserts
|
|
|
Datasheets
|
|
|
Handouts
|
|
|
SDS
|
|
|
Title
|
Journal
|
Year
|
|
Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice.
|
|
|
|
Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo.
|
|
|
|
Fibroblast growth factor 21 mediates specific glucagon actions.
|
|
|
|
Ozone induces glucose intolerance and systemic metabolic effects in young and aged brown Norway rats.
|
|
|
|
Race and sex differences in small-molecule metabolites and metabolic hormones in overweight and obese adults.
|
|
|
|
View All
|
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters