Scientific Publication References | Meso Scale Discovery

Results 1451 - 1497 of 1497 for References

References	Journal	Year
Use of pharmacokinetic/ pharmacodynamic biomarkers to support rational cancer drug development. Sarker, D., Pacey, S., Workman, P.	Biomarkers in Medicine	2007	View
Validation of amyloid-beta peptides in CSF diagnosis of neurodegenerative dementias. Bibl, M., Mollenhauer, B., Lewczuk, P., Esselmann, H., Wolf, S, Trenkwalder, C., Otto, M., Stiens G., Rüther, E., Kornhuber, J., Wiltfang, J.	Mol Psychiatry.	2007	View
A comparative assessment of g-secretase activity in transgenic and non-transgenic rodent brain. Goggi, J.L., Lewis, H.D., Mok, J., Harrison, T., Shearman, M.S., Atack, J.R., Best, J.D.	J. Neurosci Methods.	2006	View
A high throughput electrochemiluminescent cell-binding assay for therapeutic anti-CD20 antibody selection. Lu, Y., Wong, W.L., Meng, Y.G.	J Immunological Methods.	2006	View
A Model for Efficient Assay Development and Screening at a Small Research Site. Simpson, P.B.	J. Assoc. Lab Automation.	2006	View
Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Rajendran, L., Honsho, M., Zahn, T.R., Keller, P., Geiger, K.D., Verkade, P., Simons, K.	Proc Natl Acad Sci USA.	2006	View
Anticancer Activity of BIM-46174, a New Inhibitor of the Heterotrimeric Ga/Gßg Protein Complex. Prevost, G.P., Lonchampt, M.O., Holbeck, S., Attoub, S., Zaharevitz, D., Alley, M., Wright, J., Brezak, M.C., Coulomb, H., Savola, A., Huchet, M., Chaumeron, S., Nguyen, Q.D., Forgez, P., Bruyneel, E., Bracke, M., Ferrandis, E., Roubert, P., Demarquay, D., Gespach, C., Kasprzyk, P.G.	Cancer Res.	2006	View
Bile acids induce adhesion molecule expression in endothelial cells through activation of reactive oxygen species, NF-kB, and p38. Qin, P., Tang, X., Elloso, M.M., Harnish, D.C.	Am J Physiol Heart Circ Physiol.	2006	View
Biocompatibility of solid-dosage forms of anti-human immunodeficiency virus type 1 microbicides with the human cervicovaginal mucosa modeled ex vivo. Trifonova, R.T., Pasicznyk, J.M., Fichorova, R.N.	Antimicrobial Agents and Chemotherapy.	2006	View
Changes in hepatitis C virus (HCV) viral load and interferon-alpha levels in HIV/HCV-coinfected patients treated with highly active antiretroviral therapy. Bower, W.A., Culver, D.H., Castor, D., Wu, Y., James, V.N., Zheng, H., Hammer, S., Kuhnert, W.L., Williams, I.T., Bell, B.P., Vlahov, D., Dezzutti, C.S.	J Acquir Immune Defic Syndr.	2006	View
Characterization of adenosine receptors in the human bladder carcinoma T24 cell line. Phelps, T., Anthes, J.C., Correll, C.C.	Euro J Pharmacol.	2006	View
c-Met Ectodomain Shedding Rate Correlates with Malignant Potential. Athauda, G., Giubellino, A., Coleman, J.A., Horak, C., Steeg, P.S., Lee, M.J., Trepel, J., Wimberly, J., Sun, J., Coxon, A., Burgess, T.L., Bottaro, D.P.	Clin Cancer Res.	2006	View
Effect of renal function on the pharmacokinetics of palifermin. Gillespie, B., Zia-Amirhosseini, P., Salfi, M., Kakkar, T., Wang, J., Gupta, S., Smith, B., Robson, R., Sullivan J.T.	J Clin Pharmacol.	2006	View
Glia as a Therapeutic Target: Selective Suppression of Human Amyloid-Beta Induced Upregulation of Brain Proinflammatory Cytokine Production Attenuates Neurodegeneration. Ranaivo, H.R., Craft,J.M., Hu, W.H., Guo, L., Wing, L.K., Van Eldik, L.J., Watterson, D.M.	J Neuroscience.	2006	View
High-content screening analysis of the p38 pathway: profiling of structurally related p38alpha kinase inhibitors using cell-based assays. Ross S., Chen, T., Yu, V., Tudor, Y., Zhang, D., Liu, L., Tamayo, N., Dominguez, C., Powers, D.	Assay and Drug Dev Technol.	2006	View
Human amyloid beta - induced neuroinflammation is an early event in neurodegeneration. Craft, J.M., Watterson, D. M., Van Eldik, L.J.	Glia.	2006	View
Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. Khakoo, A.Y., Pati, S., Anderson, S.A., Reid, W., Elshal, M.F., Rovira, I.I., Nguyen, A.T., Malide, D., Combs, C.A., Hall, G., Zhang, J., Raffeld, M., Rogers, T.B., Stetler-Stevenson, W., Frank, J.A., Reitz. M., Finkel, T.	J Exp Med.	2006	View
Identification of Novel Brain Biomarkers. Laterza, O.F., Modur, V.R., Crimmins, D.L., Olander, J.V., Landt, Y., Lee, J., Ladenson, J.H.	Clin Chem.	2006	View
In vivo characterization of Abeta(40) changes in brain and cerebrospinal fluid using the novel gamma-secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) in the rat. Best, J.D., Jay, M.T., Otu, F., Churcher, I., Reilly, M., Morentin-Gutierrez, P., Pattison, C., Harrison, T., Shearman, M.S., Atack, J.R.	J Pharmacol Exp Ther.	2006	View
Lasofoxifene enhances vaginal mucus formation without causing hypertrophy and increases estrogen receptor [beta] and androgen receptor in rats. Wang, X., Simmons, H. A., Salatto, C. T., Cosgrove, P. G., Thompson, D. D.	Menopause.	2006	View
Pharmacokinetics, pharmacodynamics, and safety assessment of palifermin (rHuKGF) in healthy volunteers. Zia-Amirhosseini, P., Salfi, M., Leese, P., Yates, W., Danilenko, D.M., Ring, B., Cesano, A., Sullivan, J.T.	Clinical Pharmacology & Therapeutics	2006	View
Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndrome. Ryan, S., Taylor, C.T., McNicholas, W.T.	Am J Res and Crit Care Med.	2006	View
Prostacyclin antagonism reduces pain and inflammation in rodent models of hyperalgesia and chronic arthritis. Pulichino, A.M., Rowland, S., Wu, T., Clark, P., Xu, D., Mathieu, M.C., Riendeau, D., Audoly, L.P.	J Pharmacol Exp Ther.	2006	View
SB-267268, a Nonpeptidic Antagonist of vß3 and vß5 Integrins, Reduces Angiogenesis and VEGF Expression in a Mouse Model of Retinopathy of Prematurity. Wilkinson-Berka, J. L., Jones, D., Taylor, G., Jaworski, K., Kelly, D. J., Ludbrook, S. B., Willette, R. N., Kumar, S., Gilbert, R.E.	Invest Ophthalmol Vis Sci.	2006	View
Selective leukemic-cell killing by a novel functional class of thalidomide analogs. Ge, Y., Montano, I., Rustici, G., Freebern, W.J., Haggerty, C.M., Cui, W., Ponciano-Jackson, D., Chandramouli, G.V., Gardner, E.R., Figg, W.D., Abu-Asab, M., Tsokos, M., Jackson, S.H., Gardner. K.	Blood	2006	View
Toll-like receptor (TLR) 2-9 agonists-induced Cytokines & Chemokines: I. Comparison with T cell receptor-induced responses. Ghosh, T.K., Michelson, D.J., Fink, J., Solberg, J.C., Inglefield, J.R., Hook, D., Gupta, S.K., Gibson, S., Alkan, S.S.	Cell Immunol.	2006	View
Trichomonas vaginalis Lipophosphoglycan Triggers a Selective Upregulation of Cytokines by Human Female Reproductive Tract Epithelial Cells. Fichorova, R.N., Trifonova, R.T., Gilbert, R.O., Costello, C.E., Hayes, G.R., Lucas, J.J., Singh, B.N.	Infection and Immunity.	2006	View
Assays for high-throughput screening of E2 and E3 ubiquitin ligases. Kenten J.H., Davydov I.V., Safiran Y.J., Stewart D.H., Oberoi P., Biebuyck, H.A.	Methods in Enzymology.	2005	View
CSF biomarkers for Alzheimer's disease: use in early diagnosis and evaluation of drug treatment. Blennow, K.	Expert Rev Mol Diagn.	2005	View
FAPP2 is involved in the transport of apical cargo in polarized MDCK cells. Vieira, O.V., Verkade, P., Manninen, A., Simons, K.	J Cell Biol.	2005	View
Functional overexpression of gamma-secretase reveals protease-independent trafficking functions and a critical role of lipids for protease activity. Wrigley, J.D., Schurov, I., Nunn, E.J., Martin, A.C., Clarke,E.E., Ellis, S., Bonnert, T.P., Shearman, M.S., Beher, D.	J Biol Chem.	2005	View
Identification of coumarin derivatives as a novel class of allosteric MEK1 inhibitors. Han, S., Zhou, V., Pan, S., Liu, Y., Hornsby, M., McMullan, D., Klock, H.E., Haugen, J., Lesley, S.A., Gray, N., Caldwell, J., Gu, X.J.	Bioorg Med Chem Lett	2005	View
Image-based screening: a technology in transition. Ramm, P.	Curr Opin Biotechnol.	2005	View
In vitro screening for substrates of the N-end rule-dependent ubiquitylation. Davydov, I.V., Kenten, J.H., Safiran, Y.J., Nelson, S. Swenerton, R., Oberoi, P., Biebuyck, H.A.	Methods in Enzymology.	2005	View
Pharmacologic profiling of transcriptional targets deciphers promoter logic. Freebern, W.J., Haggerty, C.M., Montano, I., McNutt, M.C., Collins, I., Graham, A., Chandramouli, G.V.R., Stewart, D.H., Biebuyck, H.A., Taub, D.D., Gardner, K.	Pharmacogenomics J.	2005	View
Quantitative measurement of Changes in Amyloid-beta (40) in the Rat Brain and Cerebrospinal Fluid following Treatment with the gamma-Secretase Inhibitor LY-411575. Best, J.D., Jay, M.T., Out, F., Ma, J., Nadin, A., Ellis, S., Lewis, H.D., Pattison, C., Reilly, M., Harrison, T., Shearman, M.S., Williamson, T.L., Atack, J.R. et al.	J Pharmacol Exp Ther.	2005	View
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients. Willett, C.G., Boucher, Y., Duda, D.G., di Tomaso, E., Munn, L.L., Tong, R.T., Kozin, S.V., Petit, L., Jain, R.K., Chung, D.C., Sahani, D.V., Kalva, S.P., Cohen, K.S., Scadden, D.T., Fischman, A.J., Clark, J.W., Ryan, D.P., Zhu, A.X., Blaszkowsky, L.S., Shellito, P.C., Mino-Kenudson, M., Lauwers, G.Y.	J Clin Oncology.	2005	View
Validation of the Neuroinflammation Cycle as a Drug Discovery Target Using Integrative Chemical Biology and Lead Compound Development with an Alzheimer's Disease-Related Mouse Model. Hu, W., Ranaivo, H.R., Craft, J.M., Van Eldik, L.J., Watterson, D.M.	Curr Alzheimer's Res.	2005	View
Advancing applications of microarrays. Pluskal, M.G., Bachmann, J	Drug Discov Today.	2004	View
Assay for ubiquitin ligase activity: high-throughput screen for inhibitors of HDM2. Davydov, I.V., Woods, D., Safiran, Y.J., Oberoi, P., Fearnhead, H.O., Fang, S., Jensen, J.P., Weissman, A.M., Kenten, J.H., Vousden, K.H.	J Biomol Screen.	2004	View
Assessing cellular protein phosphorylation: high throughput drug discovery technologies. Russello, S.V.	Assay and Drug Dev Technol.	2004	View
cAMP Detection Methods in HTS: Selecting the best from the rest. Williams, C.	Nature Reviews: Drug Discovery	2004	View
Clinical and Biological Applications of ECL. Debad, J.D., Glezer, E.N., Wohlstadter, J.N., Sigal, G.B.	Electrogenerated Chemiluminescence	2004	View
High throughput screening using G-protein coupled receptors as the target. Wainer, I.W., Beigi, F., Moaddel, R.	Drug Discovery World.	2003	View
Meeting the challenges in screening. Elands, J., Botwood, M.P.	Drug Discov Today.	2002	View
Chemiluminescence, Electrogenerated Bard, A.J., Debad, J.D., Leland, J.K., Sigal, G.B., Wilbur, J.L., Wohlstadter, J.N.	Encyclopedia of Analytical Chemistry	2000	View
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