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A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Brian Grunau, Michael Asamoah-Boaheng, Pascal M Lavoie, Mohammad Ehsanul Karim, Tracy L Kirkham, Paul A Demers, Vilte Barakauskas, Ana Citlali Marquez, Agatha N Jassem, Sheila F O'Brien, Steven J Drews, Scott Haig, Sheldon Cheskes, David M Goldfarb | Clinical Infectious Diseases | 2021 | View |
Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial Peter B. Gilbert, David C. Montefiori, Adrian McDermott, Youyi Fong, David C. Benkeser, Weiping Deng, Honghong Zhou, Christopher R. Houchens, Karen Martins, Lakshmi Jayashankar, Flora Castellino, Britta Flach, Bob C. Lin, Sarah O’Connell, Charlene McDanal, Amanda Eaton, Marcella Sarzotti-Kelsoe, Yiwen Lu, Chenchen Yu, Bhavesh Borate, Lars W. P. van der Laan, Nima Hejazi, Chuong Huynh, Jacqueline Miller, Hana M. El Sahly, Lindsey R. Baden, Mira Baron, Luis De La Cruz, Cynthia Gay, Spyros Kalams, Colleen F. Kelley, Mark Kutner, Lawrence Corey, Kathleen M. Neuzil, Lindsay N. Carpp, Rolando Pajon, Dean Follmann, Ruben O. Donis, Richard A. Koup, Moderna, Inc., Coronavirus Vaccine Prevention Network (CoVPN)/Coronavirus Efficacy (COVE), United States Government (USG)/CoVPN Biostatistics Teams | medRxiv | 2021 | View |
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern Donal T. Skelly, Adam C. Harding, Javier Gilbert-Jaramillo, Michael L. Knight, Stephanie Longet, Anthony Brown, Sandra Adele, Emily Adland, Helen Brown, Medawar Laboratory Team, Tom Tipton, Lizzie Stafford, Alexander J. Mentzer, Síle A. Johnson, Ali Amini, OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group, Tiong Kit Tan, Lisa Schimanski, Kuan-Ying A. Huang, Pramila Rijal, PITCH (Protective Immunity T cells in Health Care Worker) Study Group, C-MORE/PHOSP-C Group, John Frater, Philip Goulder, Christopher P. Conlon, Katie Jeffery, Christina Dold, Andrew J. Pollard, Alex Sigal, Tulio de Oliveira, Alain R. Townsend, Paul Klenerman, Susanna J. Dunachie, Eleanor Barnes, Miles W. Carroll & William S. James | Nature Communications | 2021 | View |
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Performance of Immunoglobulin G Serology on Finger Prick Capillary Dried Blood Spot Samples to Measure SARS-CoV-2 Humoral Immunogenicity Aidan M. Nikiforuk, Brynn McMillan, Sofia R. Bartlett, Ana Citlali Márquez, Tamara Pidduck, Jesse Kustra, David M. Goldfarb, Vilte Barakauskas, Graham Sinclair, David M. Patrick, Manish Sadarangani, Gina S. Ogilvie, Muhammad Morshed, Inna Sekirov, Agatha N. Jassem | medRxiv | 2021 | View |
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Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques Romain Marlin, Véronique Godot, Sylvain Cardinaud, Mathilde Galhaut, Severin Coleon, Sandra Zurawski, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouet, Mélanie Prague, Pauline Maisonnasse, Léa Dupaty, Craig Fenwick, Thibaut Naninck, Julien Lemaitre, Mario Gomez-Pacheco, Nidhal Kahlaoui, Vanessa Contreras, Francis Relouzat, Raphael Ho Tsong Fang, Zhiqing Wang, Jerome Ellis III, Catherine Chapon, Mireille Centlivre, Inga Szurgot, Peter Liljeström, Sylvie van der Werf, Giuseppe Pantaleo, Rodolphe Thiébaut, Gerard Zurawski, Yves Levy, Roger Le Grand | Nature Portfolio | 2021 | View |
Coronavirus-Specific Antibody Cross Reactivity in Rhesus Macaques Following SARS-CoV-2 Vaccination and Infection Catherine Jacob-Dolan, Jared Feldman, Katherine McMahan, Jingyou Yu, Roland Zahn, Frank Wegmann, Hanneke Schuitemaker, Aaron G Schmidt, Dan H Barouch | Journal of Virology | 2021 | View |
Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection Najmeh Bozorgmehr, Siavash Mashhouri, Eliana Perez Rosero, Lai Xu, Shima Shahbaz, Wendy Sligl, Mohammed Osman, Demetrios J. Kutsogiannis, Erika MacIntyre, Conar R. O’Neil, Shokrollah Elahi | mBio | 2021 | View |
Infection- and vaccine-induced antibody binding and neutralization of the B.1.351 SARS-CoV-2 variant Venkata Viswanadh Edara, Carson Norwood, Katharine Floyd, Lilin Lai, Meredith E Davis-Gardner, William H Hudson, Grace Mantus, Lindsay E Nyhoff, Max W Adelman, Rebecca Fineman, Shivan Patel, Rebecca Byram, Dumingu Nipuni Gomes, Garett Michael, Hayatu Abdullahi, Nour Beydoun, Bernadine Panganiban, Nina McNair, Kieffer Hellmeister, Jamila Pitts, Joy Winters, Jennifer Kleinhenz, Jacob Usher, James B O'Keefe, Anne Piantadosi, Jesse J Waggoner, Ahmed Babiker, David S Stephens, Evan J Anderson, Srilatha Edupuganti, Nadine Rouphael, Rafi Ahmed, Jens Wrammert, Mehul S Suthar | Cell Host Microbe | 2021 | View |
Antibody Responses After a Single Dose of ChAdOx1 nCoV-19 Vaccine in Healthcare Workers Previously Infected with SARS-CoV-2 Sebastian Havervall, Ulrika Marking, Nina Greilert-Norin, Henry Ng, Ann-Christin Salomonsson, Cecilia Hellström, Elisa Pin, Kim Blom, Sara Mangsbo, Mia Phillipson, Jonas Klingström, Mikael Åberg, Sophia Hober, Peter Nilsson, Charlotte Thålin | medRxiv | 2021 | View |
mRNA vaccination compared to infection elicits an IgG-predominant response with greater SARS-CoV-2 specificity and similar decrease in variant spike recognition Katharina Röltgen, Sandra C A Nielsen, Prabhu S Arunachalam, Fan Yang, Ramona A Hoh, Oliver F Wirz, Alexandra S Lee, Fei Gao, Vamsee Mallajosyula, Chunfeng Li, Emily Haraguchi, Massa J Shoura, James L Wilbur, Jacob N Wohlstadter, Mark M Davis, Benjamin A Pinsky, George B Sigal, Bali Pulendran, Kari C Nadeau, Scott D Boyd | medRxiv | 2021 | View |
Reduced binding and neutralization of infection- and vaccine-induced antibodies to the B.1.351 (South African) SARS-CoV-2 variant Venkata Viswanadh Edara, Carson Norwood, Katharine Floyd, Lilin Lai, Meredith E. Davis-Gardner, William H. Hudson, Grace Mantus, Lindsay E. Nyhoff, Max W. Adelman, Rebecca Fineman, Shivan Patel, Rebecca Byram, Dumingu Nipuni Gomes, Garett Michael, Hayatu Abdullahi, Nour Beydoun, Bernadine Panganiban, Nina McNair, Kieffer Hellmeister, Jamila Pitts, Joy Winters, Jennifer Kleinhenz, Jacob Usher, James B. O’Keefe, Anne Piantadosi, Jesse J. Waggoner, Ahmed Babiker, David S. Stephens, Evan J. Anderson, Srilatha Edupuganti, Nadine Rouphael, Rafi Ahmed, Jens Wrammert, Mehul S. Suthar | bioRxiv | 2021 | View |
Two doses of SARS-CoV-2 vaccination induce more robust immune responses to emerging SARS-CoV-2 variants of concern than does natural infection Donal T. Skelly, Adam C. Harding, Javier Gilbert-Jaramillo, Michael L. Knight, Stephanie Longet, Anthony Brown, Sandra Adele, Emily Adland, Helen Brown, Medawar Laboratory Team, Tom Tipton, Lizzie Stafford, Síle A. Johnson, Ali Amini, OPTIC Clinical Group, Tiong Kit Tan, Lisa Schimanski, Kuan-Ying A. Huang, Pramila Rijal, PITCH Study Group, CMORE/PHOSP-C Group, John Frater, Philip Goulder, Christopher P. Conlon, Katie Jeffery, Christina Dold, Andrew J. Pollard, Alex Sigal, Tulio de Oliveira, Alain R. Townsend, Paul Klenerman, Susanna J . Dunachie, Eleanor Barnes, Miles W. Carroll, William S. James | Research Square | 2021 | View |
Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues Fan Yang, Sandra C A Nielsen, Ramona A Hoh, Katharina Röltgen, Oliver Fabian Wirz, Emily Haraguchi, Grace H Jean, Ji-Yeun Lee, Tho D Pham, Katherine J L Jackson, Krishna M Roskin, Yi Liu, Khoa Nguyen, Robert S Ohgami, Eleanor M Osborne, Kari C Nadeau, Claus U Niemann, Julie Parsonnet, Scott D Boyd | Science | 2021 | View |
Ultra-sensitive Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection for the Diagnosis of Coronavirus Disease 2019 (COVID-19) in Upper Respiratory Samples Hannah Wang, Catherine A Hogan, Michelle Verghese, Daniel Solis, Mamdouh Sibai, ChunHong Huang, James Zehnder, Malaya K Sahoo, Benjamin A Pinsky | Clinical Infectious Diseases | 2021 | View |
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations Bing Sun, Norina Tang, Michael J. Peluso, Nikita S. Iyer, Leonel Torres, Joanna L. Donatelli, Sadie E. Munter, Christopher C. Nixon, Rachel L. Rutishauser, Isabel Rodriguez-Barraquer, Bryan Greenhouse, John D. Kelly, Jeffrey N. Martin, Steven G. Deeks, Timothy J. Henrich, and Lynn Pulliam | Cells | 2021 | View |
Correlation of SARS-CoV-2 nucleocapsid antigen and RNA concentrations in nasopharyngeal samples from children and adults using an ultrasensitive and quantitative antigen assay Nira R. Pollock, Timothy J. Savage, Hanna Wardell, Rose Lee, Anu Mathew, Martin Stengelin, George B. Sigal | Journal of Clinical Microbiology | 2021 | View |
Cross-sectional prevalence of SARS-CoV-2 antibodies in healthcare workers in paediatric facilities in eight countries D Goldblatt , M Johnson, O Falup-Pecurariu, I Ivaskeviciene, V Spoulou, E Tamm, M Wagner, H J Zar, L Bleotu, R Ivaskevicius, I Papadatou, P Jõgi, J Lischka, Z Franckling-Smith, D Isarova, L Grandjean, D Zavadska | The Journal of Hospital Infection | 2021 | View |
SARS-CoV-2 elicits robust adaptive immune responses regardless of disease severity Stine SF Nielsen, Line K Vibholm, Ida Monrad, Rikke Olesen, Giacomo S Frattari, Marie H Pahus, Jesper F Højen, Jesper D Gunst, Christian Erikstrup, Andreas Holleufer, Rune Hartmann, Lars Østergaard, Ole S Søgaard, Mariane H Schleimann, Martin Tolstrup | bioRxiv | 2020 | View |
Antibody reactivity to SARS-CoV-2 is common in unexposed adults and infants under 6 months Abdelilah Majdoubi, Christina Michalski, Sarah E O'Connell, Sarah Dada, Sandeep Narpala, Jean Gelinas, Disha Mehta, Claire Cheung, Manjula Basappa, Aaron C Liu, Matthias Gorges, Vilte E Barakauskas, Jennifer Mehalko, Dominic Esposito, Inna Sekirov, Agatha N Jassem, David M Goldfarb, Daniel C Douek, Adrian B McDermott, Pascal M Lavoie | medRxiv | 2020 | View |
Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS–CoV-2 Caroline Diorio, Sarah E. Henrickson, Laura A. Vella, Kevin O. McNerney, Julie Chase, Chakkapong Burudpakdee, Jessica H. Lee, Cristina Jasen, Fran Balamuth, David M. Barrett, Brenda L. Banwell, Kathrin M. Bernt, Allison M. Blatz, Kathleen Chiotos, Brian T. Fisher, Julie C. Fitzgerald, Jeffrey S. Gerber, Kandace Gollomp, Christopher Gray, Stephan A. Grupp, Rebecca M. Harris, Todd J. Kilbaugh, Audrey R. Odom John, Michele Lambert, Emily J. Liebling, Michele E. Paessler, Whitney Petrosa, Charles Phillips, Anne F. Reilly, Neil D. Romberg, Alix Seif, Deborah A. Sesok-Pizzini, Kathleen E. Sullivan, Julie Vardaro, Edward M. Behrens, David T. Teachey, Hamid Bassiri | The Journal of Clinical Investigation | 2020 | View |
Evaluation of a novel multiplexed assay for determining IgG levels and functional activity to SARS-CoV-2 Marina Johnson, Helen R. Wagstaffe, Kimberly C. Gilmour, Annabelle Lea Mai, Joanna Lewis, Adam Hunt, Jake Sirr, Christopher Bengt, Louis Grandjean, David Goldblatt | Journal of Clinical Virology | 2020 | View |
Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates Kizzmekia S. Corbett, Barbara Flynn, Kathryn E. Foulds, Joseph R. Francica, Seyhan Boyoglu-Barnum, Anne P. Werner, Britta Flach, Sarah O’Connell, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Hanne Andersen, et al. | The New England Journal of Medicine | 2020 | View |
Humoral Response Dynamics Following Infection with SARS-CoV-2 Louis Grandjean, Anja Saso, Arturo Ortiz, Tanya Lam, James Hatcher, Rosie Thistlethwaite, Mark Harris, Timothy Best, Marina Johnson, Helen Wagstaffe, Elizabeth Ralph, Annabelle Mai, Caroline Colijn, Judith Breuer, Matthew Buckland, Kimberly Gilmour, David Goldblatt, The Co-Stars Study Team | TBD | 2020 | View |
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial Pedro M Folegatti, Katie J Ewer, Parvinder K Aley, Brian Angus, Stephan Becker, Sandra Belij-Rammerstorfer, Duncan Bellamy, Sagida Bibi, Mustapha Bittaye, Elizabeth A Clutterbuck, Christina Dold, Saul N Faust, Adam Finn, Amy L Flaxman, Bassam Hallis, Paul Heath, Daniel Jenkin, Rajeka Lazarus, Rebecca Makinson, Angela M Minassian, Katrina M Pollock, Maheshi Ramasamy, Hannah Robinson, Matthew Snape, Richard Tarrant, Merryn Voysey, Catherine Green, Alexander D Douglas, Adrian V S Hill, Teresa Lambe, Sarah C Gilbert, Andrew J Pollard | The Lancet | 2020 | View |
Reliability of self-sampling for accurate assessment of respiratory virus viral and immunologic kinetics Alpana Waghmare, Elizabeth M Krantz, Subhasish Baral, Emma Vasquez, Tillie Loeffelholz, E. Lisa Chung, Urvashi Pandey, Jane Kuypers, Elizabeth R Duke, Keith R Jerome, Alexander L Greninger, Daniel B Reeves, Florian Hladik, E Fabian Cardozo-Ojeda, Michael Boeckh, Joshua T Schiffer | TBD | 2020 | View |
Convergent Evolution in Breadth of Two V H 6-1-Encoded Influenza Antibody Clonotypes from a Single Donor Nicholas C Wu, Sarah F Andrews, Julie E Raab, Sarah O'Connell, Chaim A Schramm, Xintao Ding, Michael J Chambers, Kwanyee Leung, Lingshu Wang, Yi Zhang, John R Mascola, Daniel C Douek, Julie E Ledgerwood, Adrian B McDermott, Ian A Wilson | Cell Host & Microbe | 2020 | View |
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial Maheshi N Ramasamy, Angela M Minassian, Katie J Ewer, Amy L Flaxman, Pedro M Folegatti, Daniel R Owens, et al. | The Lancet | 2020 | View |