V-PLEX Human IFN-γ Kit


Human interferon gamma (IFN-γ), also known as immune interferon, is a glycosylated, 19.3 kDa pro-inflammatory cytokine. It exists as a non-covalently linked homodimer. IFN-γ dimers bind to the IFN-γ R1 (receptor 1), which is then triggered to bind the IFN-γ R2 (receptor 2) to form a functional receptor–ligand complex consisting of two receptor subunits. IFN-γ is produced by lymphocytes and is a potent activator of macrophages. It is involved in numerous pathways and is associated with a number of disorders including Huntington’s disease and hepatitis C. The Human IFN-γ Kit provides assay-specific components for the quantitative determination of endogenous IFN-γ in human urine, serum, plasma, and cell culture supernatants.

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