U-PLEX NHP SDF-1α Assay Overview
The U-PLEX NHP SDF-1α Assay maximizes your flexibility to design an experiment that measures SDF-1α alone or multiplexed with MSD U-PLEX assays, your own antibody pairs, or a combination of both. U-PLEX assays demonstrate high sensitivity, excellent precision, and up to 5-logs of linear dynamic range. Plates are read in less than 90 seconds on any MSD instrument, using no complicated fluidics or calibration procedures.

U-PLEX NHP SDF-1α Assay Features

• Simple protocol similar to ELISAs, yet uses less sample
• Measures non-human primate (NHP) SDF-1α in serum, plasma, and cell culture supernatants
• Create custom multiplexes using a selection of U-PLEX assays, your own antibody pairs or both

Assay Format

• Singleplex – includes MSD GOLD Small Spot Streptavidin Plates
• Multiplex – includes U-PLEX multiplex plates
• Both formats use the same assay components for efficient transfer between single- and multiplex configurations.

SDF-1α Analyte
Description - Stromal cell-derived factor 1 (SDF-1α), also known as CXCL12, is a chemokine protein that is ubiquitously expressed. SDF-1α is strongly chemotactic for T lymphocytes and monocytes. During embryogenesis, it directs the migration of hematopoietic cells from fetal liver to bone marrow and stimulates the formation of large blood vessels.

Disease Focus - Cardio-protective, inhibits HIV infection of T cells; angiogenesis (recruits endothelial progenitor cells from the bone marrow).