U-PLEX NHP IL-17F Assay

U-PLEX NHP IL-17F Assay Overview
The U-PLEX NHP IL-17F Assay maximizes your flexibility to design an experiment that measures IL-17F alone or multiplexed with other MSD U-PLEX assays, your own antibody pairs, or a combination of both. To learn more about the advantages of U-PLEX assays click here.

U-PLEX NHP IL-17F Assay Features
  • Measures NHP IL-17F in serum, plasma, and cell culture supernatants
  • Dynamic range: 155 pg/mL – 112,000 pg/mL
  • LLOD: 155 pg/mL

Typical Data
Calibration curve accuracy and precision for the U-PLEX NHP IL-17F assay were assessed and representative data are presented below.

Figure 1. U-PLEX NHP IL-17F Calibration Curve
NHP IL-17F Calibrator Curve
Figure 2. U-PLEX NHP IL-17F Data
NHP IL-17F Calibrator Curve Data
IL-17F Analyte

Description - NHP interleukin 17F (CANDF6, ML1; Gene ID: 708220) is a cross-linked homodimer, a prototypical biomarker for Th17 cells, and is closely related to IL 17A. IL-17A can pair with IL-17F to form a heterodimer of intermediate activity. IL-17F has greater affinity for IL-17RC receptor while IL-17A prefers IL-17RA, so some target-based differentiation is obtained when more than one of the possible three dimers is present. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL-2, TGF-β, and MCP-1.*

Disease Focus/Application Area - Asthma and chronic obstructive pulmonary disease (linked to mutations in IL-17F), inflammation related to non-alcoholic fatty liver disease, and rheumatoid arthritis.

*Note: IL-17F spot will capture but not detect IL-17A/F.

  • Specifications
  • Kit Contents
  • Resources
Order Details
Catalog No
Size
Price in USD
Qty
K156WAK-1
1 plate
$335.00
K156WAK-2
5 plates
$1,442.00
K156WAK-4
25 plates
$5,794.00
Customer Service/Orders


Scientific/Technical Support


Instrument Support


Company Headquarters