U-PLEX NHP IL-13 Assay


U-PLEX NHP IL-13 Assay Overview
The U-PLEX NHP IL-13 Assay maximizes your flexibility to design an experiment that measures IL-13 alone or multiplexed with other MSD U-PLEX assays, your own antibody pairs, or a combination of both. To learn more about the advantages of U-PLEX assays click here.

U-PLEX NHP IL-13 Assay Features
  • Measures NHP IL-13 in serum, plasma, and cell culture supernatants
  • Dynamic range: 1.2 pg/mL – 1,900 pg/mL
  • LLOD: 1.2 pg/mL

Typical Data
Calibration curve accuracy and precision for the U-PLEX NHP IL-13 assay were assessed and representative data are presented below.

Figure 1. U-PLEX NHP IL-13 Calibration Curve
NHP IL-13 Calibrator Curve
Figure 2. U-PLEX NHP IL-13 Data
NHP IL-13 Calibrator Curve Data
IL-13 Analyte

Description - NHP interleukin 13 (Gene ID: 574325) is a glycosylated immunoregulatory cytokine with two internal disulfide bonds. IL-13 is secreted by a variety of immune cells. IL-13 is involved in a number of biological processes, such as positive regulation of B cell proliferation, macrophage activation, immunoglobulin production, protein secretion, and phosphorylation of Stat6 protein. IL-13 initially interacts with IL-13 Rα1 to form a low affinity complex. The formation of this complex triggers association with IL-4 Rα to form a high affinity complex which also functions as the type 2 IL-4 receptor complex. In addition, IL-13 binds with high affinity to IL-13 Rα2 which is expressed as soluble intracellular protein and also on the cell surface.

Disease Focus/Application Area - Colorectal cancer and tumor metastasis, rheumatoid arthritis, psoriasis, obesity, atherogenesis, and wound healing.

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25 plates
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