U-PLEX Mouse KC Assay

MSD offers a range of individual assays utilizing U-PLEX Antibody Sets that provide a rapid and convenient method for measuring biomarkers in complex matrices. The individual assays are offered on MSD GOLD Small Spot Streptavidin Plates and use the same antibody sets and diluents as the U-PLEX multiplex assays. This allows for efficient transfer between the individual assay and a higher throughput multiplex configuration. Typical of assays developed on the MSD platform, the individual assays have high sensitivity, excellent precision, provide up to five-logs of linear dynamic range, and require minimal sample volume. Mouse KC (KC/GRO), also known as CXCL1, GROα, neutrophil-activating protein 3 (NAP-3), and melanoma growth stimulating activity alpha (MGSA-α), is a 10.2 kDa CXC chemokine. KC/GRO is produced by fibroblasts induced by platelet-derived growth factor and expressed in macrophages and endothelial cells. It produces a biological signal by binding to its receptor, CXCR2. During inflammation, it is involved in neutrophil activation and shows hematopoietic activity. Upon secretion from bone marrow stromal cells through proteolytic cleavage, the N-terminal processed form of KC (5-72) shows highly enhanced hematopoietic activity. This chemokine and its receptor are responsible for neutrophil chemotaxis in epidemic keratoconjunctivits. The U-PLEX Mouse KC/GRO Assay provides the components for the quantitative determination of both natural and recombinant KC/GRO in serum, plasma, and cell culture supernatants.

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Order Details
Catalog No
Size
Price in USD
Qty
K152VWK-1
1 plate
$309.00
K152VWK-2
5 plates
$1,313.00
K152VWK-4
25 plates
$5,794.00
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