U-PLEX Mouse IL-2 Assay


MSD offers a range of individual assays utilizing U-PLEX Antibody Sets that provide a rapid and convenient method for measuring biomarkers in complex matrices. The individual assays are offered on MSD GOLD Small Spot Streptavidin Plates and use the same antibody sets and diluents as the U-PLEX multiplex assays. This allows for efficient transfer between the individual assay and a higher throughput multiplex configuration. Typical of assays developed on the MSD platform, the individual assays have high sensitivity, excellent precision, provide up to five-logs of linear dynamic range, and require minimal sample volume. Mouse interleukin-2 (IL-2), also known as T-cell growth factor (TCGF), is a glycosylated 19.4 kDa protein produced by T-cells. IL-2 is a crucial regulator of the immune system through T-cell proliferation and other activities. The receptor for this four α-helix bundle cytokine consists of three subunits: an α subunit that is specific for IL-2; a β subunit that is a component of the IL-15 receptor; and a common gamma chain (γc/IL-2 Rγ) that is shared with the receptors for IL-4, IL-7, IL-9, IL-15, and IL-21 but does not independently interact with IL-2. IL-2 production levels are associated with HIV infection and entamoebiasis. The U-PLEX Mouse IL-2 Assay provides the components for the quantitative determination of both natural and recombinant IL-2 in serum, plasma, and cell culture supernatants.

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1 plate
5 plates
25 plates
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