U-PLEX Human TGF-β3 Assay


U-PLEX Human TGF-β3 Assay Overview
The U-PLEX Human TGF-β3 Assay maximizes your flexibility to design an experiment that measures TGF-β3 alone or multiplexed with other MSD U-PLEX assays, your own antibody pairs, or a combination of both. This assay accurately quantitates native and recombinant human TGF-β3 in multiple sample types. To learn more about the advantages of U-PLEX assays click here.

U-PLEX Human TGF-β3 Assay Features
  • Measures human TGF-β3 in serum, plasma, and cell culture supernatants
  • Dynamic range: 1.4 pg/mL – 38,600 pg/mL
  • LLOD: 1.4 pg/mL

Typical Data
Calibration curve accuracy and precision for the U-PLEX Human TGF-β3 assay were assessed and representative data are presented below.

Figure 1. U-PLEX Human TGF-β3 Calibration Curve
Human TGF-β3 Calibrator Curve
Figure 2. U-PLEX Human TGF-β3 Data
Human TGF-β3 Calibrator Curve Data
TGF-β3 Analyte

Description - Human transforming growth factor β3 (ARVD, LDS5, RNHF, ARVD1, TGF-beta3; Gene ID: 7043) is a member of at least three ligands in the TGF family that are highly pleiotropic and potent cytokines. They are secreted by almost all cell types, and as such their activity is tightly controlled and is largely non-redundant. TGFs are secreted and complexed with two other proteins, LAP and TGFBP, and require proteolytic cleavage to be active. TGF-β3 seems to play a role in the formation and maintenance of extracellular matrix and in cell-cell adhesion.

Disease Focus/Application Area - Cancer, osteoarthritis, leiomyoma, fibrosis, and chondrogenesis.

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25 plates
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