U-PLEX Human IL-5 Assay

MSD offers a range of individual assays utilizing U-PLEX Antibody Sets that provide a rapid and convenient method for measuring biomarkers in complex matrices. The individual assays are offered on MSD GOLD Small Spot Streptavidin Plates and use the same antibody sets and diluents as the U-PLEX multiplex assays. This allows for efficient transfer between the individual assay and a higher throughput multiplex configuration. Typical of assays developed on the MSD platform, the individual assays have high sensitivity, excellent precision, provide up to five-logs of linear dynamic range, and require minimal sample volume. Human interleukin-5 (IL-5), also known as B-cell growth factor II (BCGF-II) and T-cell replacing factor (TRF), is a glycosylated 15.2 kDa homodimer protein with two internal disulfide bonds. It is mainly produced by eosinophils and Th2 cells. Its main function is to induce terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. The IL-5 receptor consists of an α subunit and a βc subunit that is shared with the GM-CSF receptor. IL-5 initially binds to the α subunit with low affinity and then associates with the pre-formed βc subunit homodimer yielding a high affinity interaction. IL-5 is associated with eosinophilia, atopic dermatitis, and pulmonary fibrosis along with other disorders. The U-PLEX Human IL-5 Assay provides the components for the quantitative determination of both natural and recombinant human IL-5 in serum, plasma, and cell culture supernatants.

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Order Details
Catalog No
Size
Price in USD
Qty
K151UOK-1
1 plate
$309.00
K151UOK-2
5 plates
$1,313.00
K151UOK-4
25 plates
$5,794.00
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