MSD offers a range of individual assays utilizing U-PLEX Antibody Sets that provide a rapid and convenient method for measuring biomarkers in complex matrices. The individual assays are offered on MSD GOLD Small Spot Streptavidin Plates and use the same antibody sets and diluents as the U-PLEX multiplex assays. This allows for efficient transfer between the individual assay and a higher throughput multiplex configuration. Typical of assays developed on the MSD platform, the individual assays have high sensitivity, excellent precision, provide up to five-logs of linear dynamic range, and require minimal sample volume.
Interferon-stimulated T-cell alpha chemoattractant (CXCL11), also known as interferon gamma-inducible protein-9 (IP-9), is a cytokine chemotactic for activated T cells. Gene expression of I-TAC is mostly induced by IFN-γ and IFN-&beta, and to a lesser degree by IFN-α. I-TAC is highly expressed in peripheral blood leukocytes, pancreas and liver. I-TAC is also produced in moderate levels in thymus, spleen and lung. Low expression levels of I-TAC can also be found in small intestine, placenta, and prostate. The U-PLEX Human I-TAC Assay provides the components for the quantitative determination of both natural and recombinant human interferon-inducible T-cell a chemoattractant (I-TAC or CXCL11) in serum, plasma, and cell culture supernatants.
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Specifications
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Kit Contents
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References
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Documentation
Application(s)
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Cytokines & Chemokines
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Immunology/Inflammation
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Analyte(s)
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I-TAC
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Species
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Human
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Instrument
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MESO QuickPlex SQ 120
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SECTOR Imager 2400
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SECTOR Imager 6000
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MESO SECTOR S 600
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U-PLEX Group Compatibility
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Biomarker Group 1, Metabolic Group 1
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Plate Type
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96-well
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Goat Polyclonal
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LLOD (Sensitivity)
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1.5 pg/mL
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Dynamic Range
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1.5-5,100 pg/mL
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Sample Type
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Serum, Plasma, Cell Culture Supernatant
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Recombinant standards
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Expressed in E. coli
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Product Description
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Storage
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Quantity per Kit
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2-8°C
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1 each (1 plate size)
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2-8°C
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1 vial (1 vial)
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2-8°C
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1 each (1 plate)
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2-8°C
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1 bottle (50 mL)
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≤-10°C
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1 bottle (10 mL)
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≤-10°C
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1 bottle (8 mL)
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RT
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1 bottle (90 mL)
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Product Description
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Storage
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Quantity per Kit
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2-8°C
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1 each (5 plate size)
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2-8°C
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5 vial (1 vial)
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2-8°C
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5 each (1 plate)
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2-8°C
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1 bottle (50 mL)
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≤-10°C
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1 bottle (50 mL)
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≤-10°C
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1 bottle (40 mL)
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RT
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1 bottle (90 mL)
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Product Description
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Storage
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Quantity per Kit
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2-8°C
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5 each (5 plate size)
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2-8°C
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25 vial (1 vial)
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2-8°C
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25 each (1 plate)
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2-8°C
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5 bottle (50 mL)
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≤-10°C
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5 bottle (50 mL)
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≤-10°C
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5 bottle (40 mL)
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RT
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5 bottle (90 mL)
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Title
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Journal
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Year
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Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial
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Biomarkers of inflammation and coagulation are associated with mortality and Hepatitis flares in persons coinfected with HIV and Hepatitis viruses.
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Is maternal obesity associated with sustained inflammation in extremely low gestational age newborns?
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Barrier responses of human bronchial epithelial cells to grass pollen exposure.
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Changes in novel biomarkers of disease activity in juvenile and adult dermatomyositis are sensitive biomarkers of disease course.
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View All
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Product Inserts
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Datasheets
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SDS
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Order Details
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Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
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