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S-PLEX is MSD’s ultrasensitive assay platform. It can dramatically improve the sensitivity of immunoassays, reducing the lower limit of detection (LLOD) by 10- to 1000-fold over other assay methods. The S-PLEX Custom Human Neurology Kit enables customization of the
S-PLEX Neurology Panel 1 (human) Kit by choosing any subset of the panel’s assays. The assays can be used for quantitative measurements in the sample types listed in the “Specifications” tab below and offer detection limits in the fg/mL range.
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Specifications
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Documentation
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References
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Application(s)
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Neurobiology/Neurodegeneration
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Analyte(s)
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GFAP, Neurofilament L, Tau (total)
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Species
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Human
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Plate Type
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96-well
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Instrument(s)
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MESO SECTOR S 600MM
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MESO QuickPlex SQ 120MM
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MESO QuickPlex Q 60MM
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MESO SECTOR S 600
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MESO QuickPlex SQ 120
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SECTOR Imager 6000
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SECTOR Imager 2400
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Sample Type
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Serum, Plasma, Cell Culture Supernatant, CSF
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Schedule B Code
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3822.19.0000
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Title
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Journal
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Year
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Plasma biomarkers for diagnosis of Alzheimer’s disease and prediction of cognitive decline in individuals with mild cognitive impairment
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Quantitation of neurofilament light chain protein in serum and cerebrospinal fluid from patients with multiple sclerosis using the MSD R-PLEX NfL assay
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Associations between prognostic index scores and plasma neurofilament light in Huntington's disease
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Elevation of neural injury markers in patients with neurologic sequelae after hospitalization for SARS-CoV-2 infection
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Changes in Amyloid-β and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein.
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