R-PLEX Human CD5 Antibody Set

R-PLEX Human CD5 Antibody Set Overview
The R-PLEX Human CD5 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of CD5 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human CD5 Antibody Set Features
  • Measures human CD5 in plasma
  • Dynamic range: 5.3-50,000 pg/mL
  • Median LLOD: 5.3 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human CD5 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human CD5 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human CD5 Antibody Set
CD5 Analyte

Description - CD5 (LEU1, T1, T cell surface glycoprotein) is expressed on the surface of T cells and possibly on some B cells. Its primary role is believed to be reduction of T cell activation. CD5 is found in chronic lymphocytic leukemia and mantle cell lymphoma. It is commonly lost in cutaneous T cell lymphoma and its absence can be used as an indicator of malignancy in this condition. The absence of CD5 in T cell acute lymphoblastic leukemia is associated with a poor prognosis.

Disease Research Area - Oncology

Application Area - Oncology & Cancer

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5 plate size
50 plate size
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