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Restriction of dietary energy intake has a greater impact on bone integrity than does restriction of calcium in exercising female rats. Swift SN, Baek K, Swift JM, Bloomfield SA. | J Nutr. | 2012 | View |
Resuscitation of Traumatic Hemorrhagic Shock Patients With Hypertonic Saline - Without Dextran - Inhibits Neutrophil and Endothelial Cell Activation. Junger WG, Rhind SG, Rizoli SB, Cuschieri J, Shiu MY, Baker AJ, Li L, Shek PN, Hoyt DB, Bulger EM. | Shock. | 2012 | View |
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Safety, tolerability, pharmacokinetics, and pharmacodynamics of Losmapimod following a single intravenous or oral dose in healthy volunteers. Barbour AM, Sarov-Blat L, Cai G, Fossler MJ, Sprecher DL, Graggaber J, McGeoch AT, Maison J, Cheriyan J. | Br J Clin Pharmacol. | 2012 | View |
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Sarcoidosis and Tuberculosis Cytokine Profiles: Indistinguishable in Bronchoalveolar Lavage but Different in Blood. Thillai M, Eberhardt C, Lewin AM, Potiphar L, Hingley-Wilson S, Sridhar S, Macintyre J, Kon OM, Wickremasinghe M, Wells A, Weeks ME, Mitchell D, Lalvani A. | PLoS One | 2012 | View |
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Selective antagonist reveals the role of prostaglandin receptor EP2 in cancer cell proliferation, invasion and inflammation. Jiang J, Dingledine R. | J Pharmacol Exp Ther. | 2012 | View |
Serum and Colonic Mucosal Immune Markers in Irritable Bowel Syndrome. Chang L, Adeyemo M, Karagiannidis I, Videlock EJ, Bowe C, Shih W, Presson AP, Yuan PQ, Cortina G, Gong H, Singh S, Licudine A, Mayer M, Tache Y, Pothoulakis C, Mayer EA. | Am J Gastroenterol. | 2012 | View |
Short-term effects of air temperature on blood markers of coagulation and inflammation in potentially susceptible individuals. Schauble CL, Hampel R, Breitner S, Rückerl R, Phipps R, Diaz-Sanchez D, Devlin RB, Carter JD, Soukup J, Silbajoris R, Dailey L, Koenig W, Cyrys J, Geruschkat U, Belcredi P, Kraus U, Peters A, Schneider AE. | Occup Environ Med. | 2012 | View |
Stable Mutated tau441 Transfected SH-SY5Y Cells as Screening Tool for Alzheimer's Disease Drug Candidates. Löffler T, Flunkert S, Taub N, Schofield EL, Ward MA, Windisch M, Hutter-Paier B. | J Mol Neurosci. | 2012 | View |
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Systemic inflammation associated with severe intestinal injury in extremely low gestational age newborns. Martin CR, Bellomy M, Allred EN, Fichorova RN, Leviton A. | Fetal Pediatr Pathol. | 2012 | View |
Systemic inflammation, intraventricular hemorrhage, and white matter injury. Leviton A, Allred EN, Dammann O, Engelke S, Fichorova RN, Hirtz D, Kuban KC, Ment LR, O'shea TM, Paneth N, Shah B, Schreiber MD. | J Child Neurol. | 2012 | View |
TAP1-deficiency does not alter atherosclerosis development in Apoe-/- mice. Kolbus D, Ljungcrantz I, Söderberg I, Alm R, Björkbacka H, Nilsson J, Fredrikson GN. | PLoS One. | 2012 | View |
Targeted MET inhibition in castration-resistant prostate cancer: A randomized phase 2 study and biomarker analysis with Rilotumumab plus Mitoxantrone and Prednisone. Ryan CJ, Rosenthal M, Ng S, Alumkal J, Picus J, Gravis G, Fizazi K, Forget F, Machiels JP, Srinivas S, Zhu M, Tang R, Oliner KS, Jiang Y, Loh E, Dubey S, Gerritsen WR. | Clin Cancer Res. | 2012 | View |
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The Association of PI3 Kinase Signaling and Chemoresistance in Advanced Ovarian Cancer. Carden CP, Stewart A, Thavasu P, Kipps E, Pope L, Crespo M, Miranda S, Attard G, Garrett MD, Clarke PA, Workman P, de Bono JS, Gore M, Kaye SB, Banerji U. | Mol Cancer Ther. | 2012 | View |
The bovine CD1D gene has an unusual gene structure and is expressed but cannot present alpha-galactosylceramide with a C26 fatty acid. Nguyen TK, Koets AP, Vordermeier M, Jervis PJ, Cox LR, Graham SP, Santema WJ, Moody DB, van Calenbergh S, Zajonc DM, Besra GS, Van Rhijn I. | Int Immunol. | 2012 | View |
The CEA/CD3-Bispecific Antibody MEDI-565 (MT111) Binds a Nonlinear Epitope in the Full-Length but Not a Short Splice Variant of CEA. Peng L, Oberst MD, Huang J, Brohawn P, Morehouse C, Lekstrom K, Baeuerle PA, Wu H, Yao Y, Coats SR, Dall'acqua W, Damschroder M, Hammond SA. | PLoS One. | 2012 | View |
The characterization of fibrocyte-like cells: A novel fibroblastic cell of the placenta. Riddell MR, Winkler-Lowen B, Chakrabarti S, Dunk C, Davidge ST, Guilbert LJ. | Placenta. | 2012 | View |
The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Attenuates Inflammation and Accelerates Epithelialization in Wounds of Diabetic ob/ob Mice.1 Schürmann C, Linke A, Engelmann-Pilger K, Steinmetz C, Mark M, Pfeilschifter J, Klein T, Frank S. | J Pharmacol Exp Ther. | 2012 | View |
The DPP-4 inhibitor Linagliptin counteracts stroke in the normal and diabetic mouse brain: a comparison with Glimepiride. Darsalia V, Ortsater H, Olverling A, Darlöf E, Wolbert P, Nystrom T, Klein T, Sjoholm A, Patrone C. | Diabetes | 2012 | View |
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The glucose-lowering effects of the PDE4 inhibitors roflumilast and roflumilast-N-oxide in db/db mice. Vollert S, Kaessner N, Heuser A, Hanauer G, Dieckmann A, Knaack D, Kley HP, Beume R, Weiss-Haljiti C. | Diabetologia. | 2012 | View |
The novel DPP-4 inhibitors linagliptin and BI 14361 reduce infarct size after myocardial ischemia/reperfusion in rats. Hocher B, Sharkovska Y, Mark M, Klein T, Pfab T. | Int J Cardiol. | 2012 | View |
The release of IL-31 and IL-13 after nasal allergen challenge and their relation to nasal symptoms. Baumann R, Rabaszowski M, Stenin I, Gaertner-Akerboom M, Scheckenbach K, Wiltfang J, Schipper J, Wagenmann M. | Clin Transl Allergy. | 2012 | View |
The role of γ-Secretase Activating Protein, GSAP and imatinib in the regulation of γ-secretase activity and amyloid-β generation. Hussain I, Fabregue J, Anderes L, Ousson S, Borlat F, Eligert V, Berger S, Dimitrov M, Alattia JR, Fraering PC, Beher D. | J Biol Chem. | 2012 | View |
The role of TRKA signaling in IL-10 production by apoptotic tumor cell-activated macrophages. Ley S, Weigert A, Weichand B, Henke N, Mille-Baker B, Janssen RA, Brüne B. | Oncogene. | 2012 | View |
The TARC/sICAM5 ratio in patient plasma is a candidate biomarker for drug resistant epilepsy Pollard JR, Eidelman O, Mueller GP, Dalgard CL, Crino PB, Anderson CT, Brand EJ, Burakgazi E, Ivaturi SK, Pollard HB. | Front Neurol | 2012 | View |
The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis. Shao W, Wang D, Chiang YT, Ip W, Zhu L, Xu F, Columbus J, Belsham DD, Irwin DM, Zhang H, Wen X, Wang Q, Jin T. | Diabetes. | 2012 | View |
Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88. Kissner TL, Ruthel G, Alam S, Mann E, Ajami D, Rebek M, Larkin E, Fernandez S, Ulrich RG, Ping S, Waugh DS, Rebek J Jr, Saikh KU. | PLoS One. | 2012 | View |
Trabecular bone loss after administration of the second-generation antipsychotic risperidone is independent of weight gain. Motyl, K.J., Dick-de-Paula, I., Maloney, A.E., Lotinun, S., Bornstein, S., de Paula, F.J., Baron, R., Houseknecht, K.L., Rosen, C.J. | Bone. | 2012 | View |
Transcriptional factor regulatory factor X 6 (Rfx6) increases gastric inhibitory polypeptide (GIP) expression in enteroendocrine K-cells and is involved in GIP hypersecretion in high-fat diet-induced obesity. Suzuki K, Harada N, Yamane S, Nakamura Y, Sasaki K, Nasteska D, Joo E, Shibue K, Harada T, Hamasaki A, Toyoda K, Nagashima K, Inagaki N. | J Biol Chem. | 2012 | View |
Transcriptional activation of inflammasome components by Libby amphibole and the role of iron. Shannahan JH, Ghio AJ, Schladweiler MC, Richards JH, Andrews D, Gavett SH, Kodavanti UP. | Inhal Toxicol. | 2012 | View |
Transgenic Expression of Intraneuronal Aβ42 But Not Aβ40 Leads to Cellular Aβ Lesions, Degeneration, and Functional Impairment without Typical Alzheimer's Disease Pathology. Abramowski D, Rabe S, Upadhaya AR, Reichwald J, Danner S, Staab D, Capetillo-Zarate E, Yamaguchi H, Saido TC, Wiederhold KH, Thal DR, Staufenbiel M. | J Neurosci. | 2012 | View |
Transgenic mice with high endogenous omega-3 fatty acids are protected from spinal cord injury. Lim SN, Gladman SJ, Dyall SC, Patel U, Virani N, Kang JX, Priestley JV, Michael-Titus AT. | Neurobiol Dis. | 2012 | View |
TRPV1 deletion enhances local inflammation and accelerates the onset of systemic inflammatory response syndrome. Fernandes ES, Liang L, Smillie SJ, Kaiser F, Purcell R, Rivett DW, Alam S, Howat S, Collins H, Thompson SJ, Keeble JE, Riffo-Vasquez Y, Bruce KD, Brain SD. | J Immunol. | 2012 | View |
Underestimation of urinary biomarker-to-creatinine ratio resulting from age-related gain in muscle mass in rats. Tonomura Y, Morikawa Y, Takagi S, Torii M, Matsubara M. | Toxicology | 2012 | View |
Upregulation of IL-17, but not of IL-9, in circulating cells of CIS and relapsing MS patients. Impact of corticosteroid therapy on the cytokine network. Muls N, Jnaoui K, Dang HA, Wauters A, Van Snick J, Sindic CJ, van Pesch V. | J Neuroimmunol. | 2012 | View |
Urine Biomarkers Predict Acute Kidney Injury in Newborns. Askenazi DJ, Koralkar R, Hundley HE, Montesanti A, Parwar P, Sonjara S, Ambalavanan N. | J Pediatr. | 2012 | View |
Use of PD biomarkers to drive dose selection and early clinical decision making. Robas NM. | Bioanalysis | 2012 | View |
Validation of a novel multi-biomarker test to assess rheumatoid arthritis disease activity. Curtis JR, van der Helm-van Mil AH, Knevel R, Huizinga TW, Haney DJ, Shen Y, Ramanujan S, Cavet G, Centola M, Hesterberg LK, Chernoff D, Ford K, Shadick NA, Hamburger M, Fleischmann R, Keystone E, Weinblatt ME. | Arthritis Care Res. | 2012 | View |
Ways of coping and biomarkers of an increased atherothrombotic cardiovascular disease risk in elderly individuals. von Kanel R, Mausbach BT, Dimsdale JE, Mills PJ, Patterson TL, Ancoli-Israel S, Ziegler MG, Roepke SK, Allison M, Grant I. | Cardiovascular Psychiatry and Neurology | 2012 | View |
Workplace based mindfulness practice and inflammation: A randomized trial. Malarkey WB, Jarjoura D, Klatt M. | Brain Behav Immun. | 2012 | View |
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A Mouse GM-CSFR Antibody Attenuates Neutrophilia in Mice Exposed to Cigarette Smoke. Botelho, F.M., Nikota, J., Bauer, C., Davis, N.H., S. Cohen, E., Anderson, I.K., Coyle, A.J., Kolbeck, R., Humbles, A.A., Stämpfli, M.R., Sleeman, M.A. | Eur Respir J. | 2011 | View |
A phase 2 study of pegylated interferon α-2b (PEG-Intron®) in children with diffuse intrinsic pontine glioma. Warren, K., Bent, R., Wolters, P.L., Prager, A., Hanson, R., Packer, R., Shih, J., Camphausen, K. | Cancer. | 2011 | View |
A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis. Yellin M, Paliienko I, Balanescu A, Ter-Vartanian S, Tseluyko V, Xu LA, Tao X, Cardarelli PM, Leblanc H, Nichol G, Ancuta C, Chirieac R, Luo A. | Arthritis Rheum. | 2011 | View |
A phase II study evaluating the efficacy and safety of AMG 102 (rilotumumab) in patients with recurrent glioblastoma. Wen, P.Y., Schiff, D., Cloughesy, T.F., Raizer, J.J., Laterra, J., Smitt, M., Wolf, M., Oliner, K.S., Anderson, A., Zhu, M., Loh, E., Reardon, D.A. | Neuro Oncol. | 2011 | View |
A Pilot Study of MUC-1/CEA/TRICOM Poxviral-Based Vaccine in Patients with Metastatic Breast and Ovarian Cancer. Mohebtash, M., Tsang, K.Y., Madan, R.A., Huen, N.Y., Poole, D.J., Jochems, C., Jones, J., Ferrara, T., Heery, C.R., Arlen, P.M., Steinberg, S.M., Pazdur, M., Rauckhorst, M., Jones, E.C., Dahut, W.L., Schlom, J., Gulley, J.L. | Clin Cancer Res. | 2011 | View |
A pilot study to assess whether glucagon-like Peptide-1 protects the heart from ischemic dysfunction and attenuates stunning after coronary balloon occlusion in humans. Read, P.A., Hoole, S.P., White, P.A., Khan, F.Z., O'Sullivan, M., West, N.E., Dutka, D.P. | Circ Cardiovasc Interv. | 2011 | View |
A Role for Decorin in a Murine Model of Allergen-Induced Asthma. Marchica, C.L., Pinelli, V., Borges, M.C., Zummer, J., Narayanan, V., Iozzo, R.V., Ludwig, M.S. | Am J Physiol Lung Cell Mol Physiol. | 2011 | View |