Human Vascular Injury I Kit

Application(s)		Cardiovascular
Analyte(s)		E-Selectin, ICAM-3, P-Selectin, Thrombomodulin
Species		Human
Instrument(s)		SECTOR Imager 2400 , MESO SECTOR S 600MM , SECTOR Imager 6000 , MESO QuickPlex SQ 120MM , MESO QuickPlex SQ 120 , MESO SECTOR S 600
Plate Type		96-well
Capture Antibody		Thrombomodulin: Mouse Monoclonal ICAM-3: Mouse Monoclonal E-Selectin: Mouse Monoclonal P-Selectin: Mouse Monoclonal
Detection Antibody		Thrombomodulin: Mouse Monoclonal ICAM-3: Mouse Monoclonal E-Selectin: Mouse Monoclonal P-Selectin: Mouse Monoclonal
LLOD (Sensitivity)		Thrombomodulin: 0.08 ng/mL ICAM-3: 0.05 ng/mL E-Selectin: 0.2 ng/mL P-Selectin: 0.1 ng/mL
Dynamic Range		Thrombomodulin: 0.08-1000 ng/mL ICAM-3: 0.05-1000 ng/mL E-Selectin: 0.2-1000 ng/mL P-Selectin: 0.1-1000 ng/mL
Sample Type		Serum, Plasma
Recombinant standards		Thrombomodulin: Recombinant human Thrombomodulin from CHO cells ICAM-3: Fusion of extracellular domain of ICAM-3 (aa 1-485) with His-tagged Fc region of IgG E-Selectin: Recombinant E-Selectin minus transmembrane and cytoplasmic domains P-Selectin: Recombinant P-Selectin minus transmembrane and cytoplasmic domains
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Statement(s)		Please refer to the product insert for the storage conditions of individual kit components.
Storage Condition		Multi-Component

SDS

Title	Journal	Year
Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial G B Sigal, M R Segal, A Mathew, L Jarlsberg, M Wang, S Barbero, N Small, K Haynesworth, J L Davis, M Weiner, W C Whitworth, J Jacobs, J Schorey, D M Lewinsohn, P Nahid	EBioMedicine	2017
Decorin Mimic Inhibits Vascular Smooth Muscle Proliferation and Migration. Scott RA, Paderi JE, Sturek M, Panitch A.	PLoS One	2013
Is maternal obesity associated with sustained inflammation in extremely low gestational age newborns? van der Burg JW, Allred EN, McElrath TF, Fichorova RN, Kuban K, O'Shea TM, Dammann O, Leviton A.	Early Hum Dev.	2013
Genetic Variants in Platelet Factor 4 Modulate Inflammatory and Platelet Activation Biomarkers. Bhatnagar P, Lu X, Evans MK, Laveist TA, Zonderman AB, Carter DL, Arking DE, Fletcher CA.	Circ Cardiovasc Genet.	2012
Systemic inflammation associated with severe intestinal injury in extremely low gestational age newborns. Martin CR, Bellomy M, Allred EN, Fichorova RN, Leviton A.	Fetal Pediatr Pathol.	2012
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