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Adiponectin is a 30 kD protein that is secreted exclusively by adipocytes. It is thought to play a role in lipid and glucose metabolism. Adiponectin enhances insulin action by activating glucose uptake and fatty acid oxidation. In addition, this adipokine has potent anti-inflammatory and anti-atherosclerotic properties. Adiponectin circulates at high levels (between 2-20 µg/mL) in plasma as trimers, hexamers and high molecular weight multimers. In contrast to most adipokines, plasma adiponectin is often negatively correlated with body mass index (BMI) in humans and rodents. However, expression in various adipose tissues and disease models may vary. This kit provides the assay-specific components for the quantitative determination of adiponectin in human serum and plasma samples.
Please note: MSD has discontinued this product.
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Specifications
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Documentation
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References
Application(s)
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Metabolic
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Analyte(s)
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Adiponectin
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Species
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Human
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Instrument(s)
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SECTOR Imager 2400
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MESO SECTOR S 600MM
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SECTOR Imager 6000
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MESO QuickPlex SQ 120MM
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MESO QuickPlex SQ 120
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MESO SECTOR S 600
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Plate Type
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96-well
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Product Inserts
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Certificate of analysis
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SDS
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Blocker A
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Diluent 10, Diluent 11, Diluent 12, Diluent 13, Diluent 15, Diluent 16 and Diluent 17
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Diluent 50, Diluent 56, Diluent 61, Diluent 100, and Diluent 101
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MSD Calibrators and Controls
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Phosphate Buffer (5x)
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Read Buffer T (4x), Read Buffer S (4x) and Read Buffer S (1x)
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Title
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Journal
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Year
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Genetic Deletion and Pharmacological Inhibition of Phosphodiesterase 10A Protects Mice From Diet-Induced Obesity and Insulin Resistance.
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Elevated insulin-like growth factor binding protein-1 (IGFBP-1) in men with metastatic prostate cancer starting androgen deprivation therapy (ADT) is associated with shorter time to castration resistance and overall survival.
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Endurance training in prostate cancer patients treated with androgen deprivation therapy.
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Impaired leptin gene expression and release in cultured preadipocytes isolated from individuals born with low birth weight.
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Ozone induces glucose intolerance and systemic metabolic effects in young and aged brown Norway rats.
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View All
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