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The Rat TIM-1/KIM-1/HAVCR Assay Kit provides assay-specific components for the quantitative determination of T cell immunoglobulin and mucin domain containing molecule 1 (TIM-1) in rat urine, serum, and plasma. TIM-1 (also known as KIM-1 and HAVCR) is a type 1 transmembrane glycoprotein found on CD4+ T cells and renal proximal tubule epithelial cells. The extracellular domain of TIM-1 is made of an immunoglobulin-like domain topping a long mucin-like domain, suggesting a possible role in cell adhesion. TIM-1 is released upon certain types of acute kidney injury.
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Specifications
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Documentation
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References
Application(s)
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Toxicology
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Kidney Injury
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Analyte(s)
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HAVCR1/KIM-1
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Species
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Rat
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Plate Type
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96-well
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Instrument(s)
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MESO SECTOR S 600MM
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MESO QuickPlex SQ 120MM
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MESO SECTOR S 600
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MESO QuickPlex SQ 120
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SECTOR Imager 6000
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SECTOR Imager 2400
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Schedule B Code
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3822.19.0000
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Product Inserts
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Certificate of analysis
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SDS
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Title
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Journal
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Year
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Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes.
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Urinary biomarkers track the progression of nephropathy in hypertensive and obese rats.
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Application of emerging biomarkers of acute kidney injury in development of kidney-sparing polypeptide-based antibiotics.
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Assessment of cisplatin-induced kidney injury using an integrated rodent platform.
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Early prediction of polymyxin-induced nephrotoxicity with next generation urinary kidney injury biomarkers.
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View All
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Meso Scale Japan 株式会社