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Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke Fiona Chapman, Sarah Jean Pour, Roman Wieczorek, Edgar Trelles Sticken, Jessica Budde, Karin Röwer, Sandra Otte, Elizabeth Mason, Lukasz Czekala, Thomas Nahde, Grant O’Connell, Liam Simms and Matthew Stevenson | Frontiers in Toxicology | 2023 | View |
IL-6 as a Mediator of the Association Between Traditional Risk Factors and Future Myocardial Infarction: A Nested Case-Control Study Mulugeta M Zegeye, Jonas S O Andersson, Patrik Wennberg, Dirk Repsilber, Allan Sirsjö, Liza U Ljungberg | Arteriosclerosis, Thrombosis, and Vascular Biology | 2021 | View |
Responsiveness to curcumin intervention is associated with reduced aortic stiffness in young, obese men with higher initial stiffness. MS Campbell, AJ Berrones, IM Krishnakumar, et al. | Journal of Functional Foods. | 2017 | View |
Metformin improves the angiogenic potential of human CD34⁺ cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction. Bakhashab S, Ahmed FW, Schulten HJ, Bashir A, Karim S, Al-Malki AL, Gari MA, Abuzenadah AM, Chaudhary AG, Alqahtani MH, Lary S, Ahmed F, Weaver JU. | Cardiovasc Diabetol. | 2016 | View |
Differences in immune responses between CMV-seronegative and -seropositive patients with myocardial ischemia and reperfusion. Shmeleva EV, Boag SE, Murali S, Bennaceur K, Das R, Egred M, Purcell I, Edwards R, Todry S, Spyridopoulos I. | Immunity, Inflammation and Disease | 2015 | View |
Splenic autonomic denervation increases inflammatory status but does not aggravate atherosclerotic lesion development. Kooijman S, Meurs I, van Beek L, Khedoe PP, Giezekamp A, Pike-Overzet K, Cailotto C, van der Vliet J, van Harmelen V, Boeckxstaens G, Berbée JF, Rensen PC. | Am J Physiol Heart Circ Physiol. | 2015 | View |
A Common Polymorphism in Extracellular Superoxide Dismutase Affects Cardiopulmonary Disease Risk by Altering Protein Distribution. Hartney JM, Stidham T, Goldstrohm DA, Oberley-Deegan RE, Weaver MR, Valnickova-Hansen Z, Scavenius C, Benninger RK, Leahy KF, Johnson R, Gally F, Kosmider B, Zimmermann AK, Enghild JJ, Nozik-Grayck E, Bowler RP. | Circ Cardiovasc Genet. | 2014 | View |
Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression. Brouwers O, de Vos-Houben JMJ, Niessen PMG, Miyata T, van Nieuwenhoven F, Janssen BJA, Hageman G, Stehouwer CDA, Schalkwijk CG. | Int. J. Mol. Sci. | 2013 | View |
A multiple ascending dose study of CSL112, an infused formulation of ApoA-I. Easton R, Gille A, D'Andrea D, Davis R, | J Clin Pharmacol. | 2013 | View |
A sensitive and specific quantitation method for determination of serum cardiac Myosin binding protein-C by electrochemiluminescence immunoassay. Kuster DW, Barefield D, Govindan S, Sadayappan S. | J Vis Exp. | 2013 | View |
Cellular impedance assays for predictive preclinical drug screening of kinase inhibitor cardiovascular toxicity. Lamore SD, Kamendi HW, Scott CW, Dragan YP, Peters MF. | Toxicol Sci. | 2013 | View |
Doxycycline reduces cardiac Matrix Metalloproteinase-2 activity but does not ameliorate myocardial dysfunction during reperfusion in coronary artery bypass patients undergoing cardiopulmonary bypass. Schulze CJ, Castro MM, Kandasamy AD, Cena J, Bryden C, Wang SH, Koshal A, Tsuyuki RT, Finegan BA, Schulz R. | Crit Care Med. | 2013 | View |
Dystrophin-deficient cardiomyocytes derived from human urine: New biologic reagents for drug discovery. Guan X, Mack DL, Moreno CM, Strande JL, Mathieu J, Shi Y, Markert CD, Wang Z, Liu G, Lawlor MW, Moorefield EC, Jones TN, Fugate JA, Furth ME, Murry CE, Ruohola H. | Stem Cell Research | 2013 | View |
Susceptibility of adult and senescent Brown Norway rats to repeated ozone exposure: an assessment of behavior, serum biochemistry and cardiopulmonary function. Gordon CJ, Jarema KA, Lehmann JR, Ledbetter AD, Schladweiler MC, Schmid JE, Ward WO, Kodavanti UP, Nyska A, MacPhail RC. | Inhal Toxicol | 2013 | View |
Analytical performance validation of a coronary heart disease risk assessment multi-analyte proteomic test Nolan N, Tee L, Vijayakumar S, Burazor I, Hytopoulos E, Biggs WH, Beggs M, French C, Harrington DS. | Expert Opin Med Diagn | 2012 | View |
Arachidonate 15-Lipoxygenase Type B Knockdown Leads to Reduced Lipid Accumulation and Inflammation in Atherosclerosis. Magnusson, LU, Lundqvist A, Karlsson MN, Skalen K, Levin M, Wiklund O, Boren J, Hulten LM. | PLoS One | 2012 | View |
Biomarker panel of cardiac and skeletal muscle troponins, fatty acid binding protein 3 and myosin light chain 3 for the accurate diagnosis of cardiotoxicity and musculoskeletal toxicity in rats. Tonomura Y, Matsushima S, Kashiwagi E, Fujisawa K, Takagi S, Nishimura Y, Fukushima R, Torii M, Matsubara M. | Toxicology. | 2012 | View |
Clinical and biomarker profile of trauma-induced secondary cardiac injury. De'Ath HD, Rourke C, Davenport R, Manson J, Renfrew I, Uppal R, Davies LC, Brohi K. | Br J Surg. | 2012 | View |
Elevated remnant lipoproteins may increase subclinical CVD risk in pre-pubertal children with obesity: a case-control study. Wang Y, Pendlebury C, Dodd MM, Maximova K, Vine DF, Jetha MM, Ball GD, Proctor SD. | Pediatr Obes. | 2012 | View |
Fibromodulin deficiency reduces low-density lipoprotein accumulation in atherosclerotic plaques in apolipoprotein E-null mice. Shami A, Gustafsson R, Kalamajski S, Krams R, Segers D, Rauch U, Roos G, Nilsson J, Oldberg A, Hultgårdh-Nilsson A. | Arterioscler Thromb Vasc Biol | 2012 | View |
Genetic Variants in Platelet Factor 4 Modulate Inflammatory and Platelet Activation Biomarkers. Bhatnagar P, Lu X, Evans MK, Laveist TA, Zonderman AB, Carter DL, Arking DE, Fletcher CA. | Circ Cardiovasc Genet. | 2012 | View |
In vitro and clinical studies examining the expression of osteopontin in cigarette smoke-exposed endothelial cells and cigarette smokers. Bishop E, Theophilus EH, Fearon IM. | BMC Cardiovascular Disorders | 2012 | View |
Increased inflammation in atherosclerotic lesions of diabetic Akita-LDLr−/− mice compared to nondiabetic LDLr−/− mice Engelbertsen D, To F, Duner P, Kotova O, Soderberg I, Alm R, Gomez MF, Nilsson J, Bengtsson E. | Experimental Diabetes Research | 2012 | View |
Modest elevation in BNP in asymptomatic hypertensive patients reflects sub-clinical cardiac remodeling, inflammation and extracellular matrix changes. Phelan D, Watson C, Martos R, Collier P, Patle A, Donnelly S, Ledwidge M, Baugh J, McDonald K. | PLoS One. | 2012 | View |
Pharmacokinetics and biodistribution of a human monoclonal antibody to oxidized LDL in cynomolgus monkey using PET imaging. Kamath AV, Williams SP, Bullens S, Cowan KJ, Stenberg Y, Cherry SR, Rendig S, Kukis DL, Griesemer C, Damico-Beyer LA, Bunting S. | PLoS One | 2012 | View |