Placenta growth factor (PlGF, PGF, PGFL, PLGF) is a member of the PDGF/VEGF family of growth factors active in angiogenesis, vasculogenesis, and endothelial cell growth. PlGF was first identified in human placenta.It binds to and signals through VEFR-1/flt-1 receptor. PlGF plays a role in inflammatory processes by attracting and activating monocytes. The source of PlGF during pregnancy is the placental trophoblast. PlGF is also expressed in the brain and participates in promoting adult pathological angiogenesis. It has been shown that PlGF expression by melanoma cells can be linked to tumor growth.


PlGF Singleplex Products

Our PlGF immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of PlGF. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.


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