IL-6

Interleukin-6 (IL-6), also known as B-cell stimulatory factor 2 (BSF-2), CTL differentiation factor (CDF), hybridoma growth factor, and Interferon beta-2 (IFN-β2) is a cytokine with two disulfide bonds that is secreted mainly by T cells and macrophages. IL-6 is involved in numerous biological processes including inflammation, aging, cell growth, apoptosis, and bone remodeling. IL-6 is released from muscle cells during exercise in response to muscle contraction. IL-6 induces acute phase response and plays an essential role in differentiating B cells into Ig secreting cells. The receptor for IL-6 consists of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 binding to IL-6R triggers the binding of the IL-6-receptor complex to gp130 and the homodimerization of gp130. IL-6 is involved in osteoporosis, pulmonary fibrosis, liver cirrhosis, ischemia, and berylliosis among other disorders.

 

IL-6 Singleplex Products

Our IL-6 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of IL-6. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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IL-6 Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

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