BAFF-R

B-Cell Activating Factor Receptor (BAFFR, CD268, CVID4, BAFF-R, BROMIX,TNFRSF13C) is one of three known receptors for BAFF, which regulates B- and T-cell function. BAFF-R is required for B-cell maturation and is predominantly expressed on peripheral B-cells. BAFF-R has also been associated with costimulation of T-cells. BAFF-R is encoded by the TNFRSF13C gene. BAFF/BAFF-R signaling has been widely implicated to play a role in autoimmune conditions in both humans and mice. BAFF levels are significantly elevated in patients with systemic lupus erythematosus, systemic sclerosis, and rheumatoid arthritis.

 

BAFF-R Singleplex Products

Our BAFF-R immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of BAFF-R. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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