Aβ42

β-amyloid (Aβ) peptides are the major components of the senile plaques that are associated with Alzheimer’s disease. In healthy individuals, Aβ peptides are present only in small quantities as soluble monomers that circulate in the cerebrospinal fluid (CSF) and blood. In Alzheimer’s patients, Aβ levels increase significantly, and they begin to accumulate as insoluble fibrillary plaques. Different Aβ species originate from proteolytic cleavage of the amyloid precursor protein (APP). It has been shown that the quantity of Aβ correlates with the clinical status of the patient and may be closely related to disease state.

 

Aβ42 Singleplex Products

Our Aβ42 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of Aβ42. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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Aβ42 Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

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