Click image to enlarge
Please note: This V-PLEX kit is currently being redeveloped. In the interim, MSD is offering to fulfill your order with the corresponding product on our U-PLEX platform. We recommend purchase of the
U-PLEX Mouse IL-17E/IL-25 Assay.
V-PLEX Mouse IL-17E/IL-25 Kit Overview The V-PLEX Mouse IL-17E/IL-25 Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Mouse IL-17E/IL-25 Kit enables the sensitive detection of IL-17E/IL-25 in multiple sample types including serum, plasma, urine, and cell culture supernatant. To learn more about the advantages of V-PLEX assays
click here.
The V-PLEX Mouse IL-17E/IL-25 assay is available as an individual assay as well as in a multiplex combination with other Th17-related analytes in the V-PLEX Th17 Panel 1 Mouse Kit (catalog # K15246G, K15246D).
All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis.
V-PLEX Mouse IL-17E/IL-25 Assay Features - Validated to measure mouse IL-17E/IL-25 in serum, plasma, urine, and cell culture supernatant
- Dynamic range: 0.630 – 3,300 pg/mL
- LLOQ: 4.54 pg/mL
Typical Data Calibration curve for the V-PLEX Mouse IL-17E/IL-25 Kit was assessed and representative data is presented below.
Figure 1. V-PLEX Mouse IL-17E/IL-25 Kit Calibration Curve IL-17E/IL-25 Analyte
Description - Mouse IL-17E (also known as IL-25) is one of 6 homologically related peptides in the IL-17 family. It is a mediator of allergic reactions and protects against intestinal parasites including helminths. IL-17E is upregulated in epithelial cells, TH2 cells, eosinophils and basophils and may contribute to chronic inflammatory responses. It activates NF-κB and stimulates IL-8 production. This is in contrast to other IL-17 family members that promote TH1 and Th17-like responses.
Disease Research Area - Autoimmune & Inflammation
Application Area - Cytokines & Chemokines, Inflammatory Injury
-
-
Specifications
-
-
Documentation
-
References
Application(s)
|
|
Cytokines & Chemokines
,
Immunology/Inflammation
,
Toxicology
|
|
Analyte(s)
|
|
IL-17E/IL-25
|
|
Species
|
|
Mouse
|
|
Instrument(s)
|
|
SECTOR Imager 2400
,
MESO SECTOR S 600MM
,
SECTOR Imager 6000
,
MESO QuickPlex SQ 120MM
,
MESO QuickPlex SQ 120
,
MESO SECTOR S 600
|
|
Plate Type
|
|
96-well
|
|
Capture Antibody
|
|
Rat Monoclonal
|
|
Detection Antibody
|
|
Goat Polyclonal
|
|
LLOD (Sensitivity)
|
|
0.630 pg/mL
|
|
Dynamic Range
|
|
0.630 – 3,300 pg/mL
|
|
Sample Type
|
|
Cell Culture Supernatant, Plasma, Serum, Urine
|
|
Recombinant standards
|
|
Recombinant Expressed in E. coli
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
Storage Condition
|
|
Multi-Component
|
|
Gene ID(s)
|
|
140806
|
|
UniProt ID(s)
|
|
0
|
|
Product Inserts
|
|
|
Certificate of analysis
|
|
|
SDS
|
|
|
Title
|
Journal
|
Year
|
|
Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity
|
|
|
|
Protection Against Lethal Multidrug-Resistant Bacterial Infections Using Macrophage Cell Therapy
|
|
|
|
|
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters