V-PLEX Mouse IL-17E/IL-25 Kit

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Please note: This V-PLEX kit is currently being redeveloped. In the interim, MSD is offering to fulfill your order with the corresponding product on our U-PLEX platform. We recommend purchase of the  U-PLEX Mouse IL-17E/IL-25 Assay.

V-PLEX Mouse IL-17E/IL-25 Kit Overview
The V-PLEX Mouse IL-17E/IL-25 Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Mouse IL-17E/IL-25 Kit enables the sensitive detection of IL-17E/IL-25 in multiple sample types including serum, plasma, urine, and cell culture supernatant. To learn more about the advantages of V-PLEX assays click here.

The V-PLEX Mouse IL-17E/IL-25 assay is available as an individual assay as well as in a multiplex combination with other Th17-related analytes in the V-PLEX Th17 Panel 1 Mouse Kit (catalog # K15246G, K15246D).

All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis.

V-PLEX Mouse IL-17E/IL-25 Assay Features
  • Validated to measure mouse IL-17E/IL-25 in serum, plasma, urine, and cell culture supernatant
  • Dynamic range: 0.630 – 3,300 pg/mL
  • LLOQ: 4.54 pg/mL

Typical Data
Calibration curve for the V-PLEX Mouse IL-17E/IL-25 Kit was assessed and representative data is presented below.

Figure 1. V-PLEX Mouse IL-17E/IL-25 Kit Calibration Curve
Calibration Curve for V-PLEX Mouse IL-17E/IL-25 Kit
IL-17E/IL-25 Analyte

Description - Mouse IL-17E (also known as IL-25) is one of 6 homologically related peptides in the IL-17 family. It is a mediator of allergic reactions and protects against intestinal parasites including helminths. IL-17E is upregulated in epithelial cells, TH2 cells, eosinophils and basophils and may contribute to chronic inflammatory responses. It activates NF-κB and stimulates IL-8 production. This is in contrast to other IL-17 family members that promote TH1 and Th17-like responses.

Disease Research Area - Autoimmune & Inflammation

Application Area - Cytokines & Chemokines, Inflammatory Injury

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