V-PLEX Mouse IL-17A Kit

V-PLEX Mouse IL-17A Kit Overview
The V-PLEX Mouse IL-17A Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Mouse IL-17A Kit enables the sensitive detection of IL-17A in multiple sample types including serum, plasma, urine, and cell culture supernatant. To learn more about the advantages of V-PLEX assays click here.

The V-PLEX Mouse IL-17A assay is available as an individual assay as well as in a multiplex combination with other Th17-related analytes in the V-PLEX Th17 Panel 1 Mouse Kit (catalog # K15246G, K15246D).

All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis.

V-PLEX Mouse IL-17A Assay Features
  • Validated to measure mouse IL-17A in serum, plasma, urine, and cell culture supernatant
  • Dynamic range: 0.056 – 360 pg/mL
  • LLOQ: 0.255 pg/mL

Typical Data
Calibration curve for the V-PLEX Mouse IL-17A Kit was assessed and representative data is presented below.

Figure 1. V-PLEX Mouse IL-17A Kit Calibration Curve
Calibration Curve for V-PLEX Mouse IL-17A Kit
IL-17A Analyte

Description - Mouse IL-17A (CTLA-8), is a glycosylated 17.5 kDa homodimer protein with two disulfide bonds. It induces stromal cells to produce proinflammatory and hematopoietic cytokines, and it enhances the surface expression of Intracellular adhesion molecule 1 (ICAM-1) in fibroblasts. IL-17A is a positive regulator of IL-23 production and is a key component of the Th17 pathway. IL-17A can dimerize with IL-17F. The receptor for the IL-17A, IL-17F, and IL-17A/IL-17F hetereodimer consists of IL-17RA and IL-17RC.

Disease Research Area - Autoimmune & Inflammation, Infectious Diseases, Metabolic Diseases

Application Area - Cytokines & Chemokines, Inflammatory Injury

  • Specifications
  • Kit Contents
  • References
  • Resources
Order Details
Catalog No
Size
Price in USD
Qty
K152RFD-1
1 plate
$450.00
K152RFD-2
5 plates
$1,913.00
K152RFD-4
25 plates
$8,438.00
Customer Service/Orders


Scientific/Technical Support


Instrument Support


Company Headquarters