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The V-PLEX COVID-19 Respiratory Panel 3 (ACE2) Kit is a multiplex neutralization assay that measures the antibodies capable of blocking the binding of angiotensin-converting enzyme 2 (ACE2) to the SARS-CoV-2 Spike and RBD antigens. The Panel serves as a high-throughput alternative to traditional neutralization assays. It includes 15 important antigens related to SARS-CoV-2, SARS-1, circulating Coronaviruses, and other respiratory diseases: HCoV-229E Spike, Flu A/Hong Kong H3, Flu A/Michigan H1, Flu A/Shanghai H7, Flu B/Brisbane HA, Flu B/Phuket HA, HCoV-HKU1 Spike, HCoV-OC43 Spike, HCoV-NL63 Spike, RSV Pre-Fusion F, SARS-CoV-1 Spike, SARS-CoV-2 N, MERS-CoV Spike, SARS-CoV-2 S1 RBD, and SARS-CoV-2 Spike.
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Specifications
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Documentation
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References
Analyte(s)
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Flu A/Hong Kong/2014 H3, Flu A/Michigan/2015 H1, Flu A/Shanghai/2013 H7, Flu B/Brisbane/2008 HA, Flu B/Phuket/2013 HA, HCoV-229E Spike, HCoV-HKU1 Spike, HCoV-NL63 Spike, HCoV-OC43 Spike, MERS-CoV Spike, RSV Pre-Fusion F, SARS-CoV-1 Spike, SARS-CoV-2 N, SARS-CoV-2 S1 RBD, SARS-CoV-2 Spike
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Species
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Human
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Instrument(s)
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SECTOR Imager 2400
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MESO QuickPlex SQ 120MM
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MESO SECTOR S 600
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SECTOR Imager 6000
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MESO SECTOR S 600MM
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MESO QuickPlex SQ 120
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Plate Type
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96-well
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Sample Type
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Serum, Plasma
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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2-8 °C
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Schedule B Code
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3002.15.0100
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Title
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Journal
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Year
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Durability of neutralizing RSV antibodies following nirsevimab administration and elicitation of the natural immune response to RSV infection in infants
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Diagnostic accuracy of the ultrasensitive S-PLEX SARS-CoV-2 N electrochemiluminescence immunoassay
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IgG Anti-Spike Antibodies and Surrogate Neutralizing Antibody Levels Decline Faster 3 to 10 Months After BNT162b2 Vaccination Than After SARS-CoV-2 Infection in Healthcare Workers
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Immune responses after omicron infection in triple-vaccinated health-care workers with and without previous SARS-CoV-2 infection
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Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccination
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Scientific/Technical Support
Instrument Support
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