MSD offers a range of individual assays utilizing U-PLEX Antibody Sets that provide a rapid and convenient method for measuring biomarkers in complex matrices. The individual assays are offered on MSD GOLD Small Spot Streptavidin Plates and use the same antibody sets and diluents as the U-PLEX multiplex assays. This allows for efficient transfer between the individual assay and a higher throughput multiplex configuration. Typical of assays developed on the MSD platform, the individual assays have high sensitivity, excellent precision, provide up to five-logs of linear dynamic range, and require minimal sample volume. MCP-4 (CCL13), also known as CK-beta 10, NCC-1, and small-inducible cytokine A13 (SCYA13), is an 11 kDa chemotactic factor that attracts monocytes, lymphocytes, basophils, and eosinophils. MCP-4 binds to CCR2B and CCR3 and plays a major role in the recruitment of leukocytes in allergic and non-allergic inflammation. It is involved in rheumatoid arthritis and chronic obstructive pulmonary disease. The U-PLEX NHP MCP-4 Assay provides the components for the quantitative determination of both natural and recombinant MCP-4 in Cynomolgus monkey and Rhesus monkey serum, plasma, and cell culture supernatants.

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