MSD offers a range of individual assays utilizing U-PLEX Antibody Sets that provide a rapid and convenient method for measuring biomarkers in complex matrices. The individual assays are offered on MSD GOLD Small Spot Streptavidin Plates and use the same antibody sets and diluents as the U-PLEX multiplex assays. This allows for efficient transfer between the individual assay and a higher throughput multiplex configuration. Typical of assays developed on the MSD platform, the individual assays have high sensitivity, excellent precision, provide up to five-logs of linear dynamic range, and require minimal sample volume. Interleukin-7 (IL-7) is a glycosylated 20.2 kDa protein with three disulfide bonds. It is a hematopoietic growth factor that stimulates the proliferation of lymphoid progenitors and plays a role in proliferation of B cells. It is involved in a number of biological processes such as cell-cell signaling, negative regulation of apoptosis, and humoral immune response. The receptor for IL-7 consists of IL-7Rα and the common γ chain (cγ), which is shared with IL-2, IL-4, IL-9, and IL-15. It is involved in numerous disorders such as multiple sclerosis. The U-PLEX NHP IL-7 Assay provides the components for the quantitative determination of both natural and recombinant IL-7 in Cynomolgus monkey and Rhesus monkey serum, plasma, and cell culture supernatants.

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