U-PLEX Mouse IL-17A Assay

U-PLEX Mouse IL-17A Assay Overview
The U-PLEX Mouse IL-17A Assay maximizes your flexibility to design an experiment that measures IL-17A alone or multiplexed with MSD U-PLEX assays, your own antibody pairs, or a combination of both. U-PLEX assays demonstrate high sensitivity, excellent precision, and up to 5-logs of linear dynamic range. Plates are read in less than 90 seconds on any MSD instrument, using no complicated fluidics or calibration procedures.

U-PLEX Mouse IL-17A Assay Features
  • Simple protocol similar to ELISAs, yet uses less sample
  • Measures mouse IL-17A in serum, plasma, and cell culture supernatants
  • Create custom multiplexes using a selection of U-PLEX assays, your own antibody pairs or both

Assay Format
  • Singleplex – includes MSD GOLD Small Spot Streptavidin Plates
  • Multiplex – includes U-PLEX multiplex plates
  • Both formats use the same assay components for efficient transfer between single- and multiplex configurations.

IL-17A Analyte
Description- Mouse IL-17A (CTLA-8), is a glycosylated 17.5 kDa homodimer protein with two disulfide bonds. It induces stromal cells to produce proinflammatory and hematopoietic cytokines, and it enhances the surface expression of Intracellular adhesion molecule 1 (ICAM-1) in fibroblasts. IL-17A is a positive regulator of IL-23 production and is a key component of the Th17 pathway. IL-17A can dimerize with IL-17F*. The receptor for the IL-17A, IL-17F, and IL-17A/IL-17F hetereodimer consists of IL-17RA and IL-17RC.

Disease Focus - Rhinovirus infection, Sjogren’s syndrome, many autoimmune disorders including asthma, rheumatoid arthritis and inflammatory bowel disease (IBD).

*NOTE: U-PLEX Mouse IL-17A Assay should not be combined in the same plate with the U-PLEX Mouse IL-17F if IL-17A/F is present.

  • Specifications
  • Kit Contents
  • References
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Order Details
Catalog No
Size
Price in USD
Qty
K152UTK-1
1 plate
$309.00
K152UTK-2
5 plates
$1,313.00
K152UTK-4
25 plates
$5,794.00
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