The U-PLEX platform makes it easy to create multiplex immunoassays. Using two simple tools - a 10-spot U-PLEX plate and unique Linkers - you can build multiplex panels for any combination of analytes. The analytes in the U-PLEX menu are organized into U-PLEX Groups. Analytes within the same U-PLEX Group have been tested for multiplex compatibility and can be combined in panels with confidence. The U-PLEX Biomarker Group 1 (ms) contains 35 biomarkers (Table 1). It is a mix of traditional and emerging biomarkers related to inflammation and the immune system. This U-PLEX Group can be ordered as a full panel (35 markers) or as one or more smaller panels that are subsets of the full panel. The full panel is available as a catalog product
K15083K. Ordering any subset of assays from the U-PLEX Biomarker Group 1 (ms) is simple and can be done online with MSD’s
U-PLEX Assay Designer.
| Analyte | LLOD - ULOD | units |
| EPO | 4.5 - 12,500 | pg/mL |
| GM-CSF | 0.16 - 1,000 | pg/mL |
| IFN-γ | 0.16 - 2,900 | pg/mL |
| IL-1β | 3.1 - 13,000 | pg/mL |
| IL-2 | 1.1 - 10,900 | pg/mL |
| IL-4 | 0.56 - 10,000 | pg/mL |
| IL-5 | 0.63 - 2,800 | pg/mL |
| IL-6 | 4.8 - 16,000 | pg/mL |
| IL-9 | 1.4 - 8,900 | pg/mL |
| IL-10 | 3.8 - 22,800 | pg/mL |
| IL-12/IL-23p40 | 1.4 - 20,400 | pg/mL |
| IL-12p70 | 48 - 89,000 | pg/mL |
| IL-13 | 2.7 - 22,800 | pg/mL |
| IL-15 | 24 - 131,000 | pg/mL |
| IL-16 | 3.6 - 6,250 | pg/mL |
| IL-17A | 0.30 - 2,150 | pg/mL |
| IL-17A/F | 0.61 - 10,600 | pg/mL |
| IL-17C | 2.3 - 45,600 | pg/mL |
| IL-17E/IL-25 | 1.6 - 18,900 | pg/mL |
| Analyte | LLOD - ULOD | units |
| IL-17F | 24 - 52,600 | pg/mL |
| IL-21 | 6.5 - 40,600 | pg/mL |
| IL-22 | 1.2 - 1,850 | pg/mL |
| IL-23 | 4.9 - 20,400 | pg/mL |
| IL-27p28/IL-30 | 8.7 - 73,200 | pg/mL |
| IL-31 | 45 - 66,200 | pg/mL |
| IL-33 | 2.2 - 36,000 | pg/mL |
| IP-10 | 0.50 - 4,900 | pg/mL |
| KC/GRO | 0.40 - 2,400 | pg/mL |
| MCP-1 | 1.4 - 1,400 | pg/mL |
| MIP-1α | 0.21 - 2,100 | pg/mL |
| MIP-1β | 13 - 30,800 | pg/mL |
| MIP-2 | 0.30 - 2,000 | pg/mL |
| MIP-3α | 0.10 - 2,500 | pg/mL |
| TGF-β1 | 37 - 38,900 | pg/mL |
| TGF-β2 | 2.5 - 39,300 | pg/mL |
| TGF-β3 | 2.5 - 40,000 | pg/mL |
| TNF-α | 1.3 - 6,200 | pg/mL |
| VEGF-A | 0.77 - 12,100 | pg/mL |
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Specifications
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Documentation
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References
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Application(s)
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Cytokines & Chemokines
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Immunology/Inflammation
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Analyte(s)
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EPO, GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, IL-17A/F, IL-17C, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-27p28/IL-30, IL-31, IL-33, IP-10, KC/GRO, MCP-1, MIP-1α, MIP-1β, MIP-2, MIP-3α, TGF-β1, TGF-β2, TGF-β3, TNF-α, VEGF-A
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Species
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Mouse
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Instrument
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MESO QuickPlex SQ 120
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SECTOR Imager 2400
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SECTOR Imager 6000
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MESO SECTOR S 600
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Plate Type
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96-well
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Sample Type
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Serum, Plasma, Cell Culture Supernatant
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Product Inserts
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Product Highlights
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Handouts
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Datasheets
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View More
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Title
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Journal
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Year
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Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity
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Early and late effects of maternal experience on hippocampal neurogenesis, microglia, and the circulating cytokine milieu
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Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial
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CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer’s disease
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Cytokine biomarkers in tear film for primary open-angle glaucoma
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