R-PLEX Rat Leptin Antibody Set

R-PLEX Rat Leptin Antibody Set Overview
The R-PLEX Rat Leptin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Leptin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Rat Leptin Antibody Set Features
  • Measures rat Leptin in serum and plasma
  • Dynamic range: 24 - 100,000 pg/mL
  • Median LLOD: 24 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Rat Leptin Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Rat Leptin Antibody Set Calibration Curve
Calibration Curve for R-PLEX Rat Leptin Antibody Set
Leptin Analyte

Description - Leptin (OB, OBS, LEP, LEPD) is released by adipocytes. Leptin plays a key role in metabolism and regulation of adipose tissue. It is released in amounts mirroring overall body fat stores and acts on neurons and hypothalamic receptors, thereby influencing the brain’s perception of appetite. The absence of leptin leads to uncontrolled food intake and resulting obesity. Leptin may be a critical regulator of obesity that is often accompanied by insulin resistance and hyperinsulinemia.

Disease Research Area - Metabolic Diseases

Application Area - Metabolic

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5 plate size
50 plate size
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