R-PLEX Mouse Leptin Antibody Set Overview
The R-PLEX Mouse Leptin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Leptin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
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R-PLEX Mouse Leptin Antibody Set Features
- Measures mouse Leptin in serum and plasma
- Dynamic range: 13 - 200,000 pg/mL
- Median LLOD: 13 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data
Calibration curve for the R-PLEX Mouse Leptin Antibody Set was assessed and representative data are presented below.
Figure 1. R-PLEX Mouse Leptin Antibody Set Calibration Curve
Leptin Analyte
Description - Leptin (OB, OBS, LEP, LEPD) is released by adipocytes. Leptin plays a key role in metabolism and regulation of adipose tissue. It is released in amounts mirroring overall body fat stores and acts on neurons and hypothalamic receptors, thereby influencing the brain’s perception of appetite. The absence of leptin leads to uncontrolled food intake and resulting obesity. Leptin may be a critical regulator of obesity that is often accompanied by insulin resistance and hyperinsulinemia.
Disease Research Area - Metabolic Diseases
Application Area - Metabolic
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Recommended Components
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Specifications
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Kit Contents
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References
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Documentation
You will need plates, diluents, and read buffer to run your assay. Please select from the below menu.
R-PLEX Sets are intended to be used with other MSD components such as plates, diluents and MSD Read Buffer. If you don’t already have these items, you can purchase them along with your Antibody Set(s). The “Recommended Components” tab provides helpful suggestions or you can call MSD Customer Service (Phone number) for assistance. R-PLEX Sets can also be used with other antibody sets such as U-PLEX antibody sets (make a link to UPLEX landing page) for multiplex measurements.
Catalog No.
Product Name
Size
R50AA-4
R50AA-4
R92TG-3
L45SA-1
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Application(s)
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Metabolic
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Analyte(s)
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Leptin
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Species
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Mouse
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Capture Antibody
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Rat monoclonal
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Detection Antibody
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Goat polyclonal
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Dynamic Range
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13 - 200,000 pg/mL
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Sample Type
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Serum, Plasma
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LLOD (Sensitivity)
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13 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Gene ID(s)
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16846
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UniProt ID(s)
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P41160
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Assay Diluent(s)
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Diluent 100
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Antibody Diluent(s)
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Diluent 17
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Product Description
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Storage
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Quantity per Kit
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Mouse Leptin Antibody Set (5 Plate Size)
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2-8°C
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1 ea
(5 plate size)
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Mouse Leptin Calibrator
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≤-70°C
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5 vial
(1 vial)
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Product Description
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Storage
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Quantity per Kit
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Mouse Leptin Antibody Set (5 Plate Size)
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2-8°C
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10 ea
(5 plate size)
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Mouse Leptin Calibrator
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≤-70°C
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50 vial
(1 vial)
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Title
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Journal
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Year
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Genetic Deletion and Pharmacological Inhibition of Phosphodiesterase 10A Protects Mice From Diet-Induced Obesity and Insulin Resistance.
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A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study.
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Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis.
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Elevated insulin-like growth factor binding protein-1 (IGFBP-1) in men with metastatic prostate cancer starting androgen deprivation therapy (ADT) is associated with shorter time to castration resistance and overall survival.
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Endurance training in prostate cancer patients treated with androgen deprivation therapy.
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Product Inserts
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SDS
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Handouts
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Datasheets
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Order Details
Catalog No
Size
Price in USD
Qty
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Instrument Support
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