R-PLEX Human TLR1 Antibody Set

R-PLEX Human TLR1 Antibody Set Overview
The R-PLEX Human TLR1 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of TLR1 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human TLR1 Antibody Set Features
  • Measures human TLR1 in serum, plasma, and cell lysate
  • Dynamic range: 8.6-25,000 pg/mL
  • Median LLOD: 8.6 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human TLR1 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human TLR1 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human TLR1 Antibody Set
TLR1 Analyte

Description - Toll-like receptor 1 (TLR1, CD281, TIL, LPRS5) plays a fundamental role in activation of innate immunity. TLRs recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of an effective immune response. TLR1 has specificity for gram-positive bacteria. Particular sites of expression include the gut epithelia where it participates in managing the microbiota, and on macrophages and neutrophils.

Disease Research Area - Oncology

Application Area - Immunology/Inflammation, Immuno-Oncology

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5 plate size
50 plate size
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