R-PLEX Human PlGF Antibody Set

R-PLEX Human PlGF Antibody Set Overview
The R-PLEX Human PlGF Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of PlGF in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human PlGF Antibody Set Features
  • Measures human PlGF in serum, plasma, and urine
  • Dynamic range: 0.43 - 2,000 pg/mL
  • Median LLOD: 0.43 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human PlGF Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human PlGF Antibody Set Calibration Curve
Calibration curve for R-PLEX Human PlGF Antibody Set
PlGF Analyte

Description - Placenta growth factor (PlGF, PGF, PGFL, PLGF) is a member of the PDGF/VEGF family of growth factors active in angiogenesis, vasculogenesis, and endothelial cell growth. PlGF was first identified in human placenta. PlGF binds and signals through VEFR-1/flt-1 receptor. PlGF plays a role in inflammatory processes by attracting and activating monocytes. The source of PlGF during pregnancy is the placental trophoblast, and is a biomarker for preeclampsia. PlGF is also expressed in the brain and participates in promoting adult pathological angiogenesis. It has been shown that PlGF expression by melanoma cells can be linked to tumor growth.

Disease Research Area - Preeclampsia, Angiogenesis

Application Area - Angiogenesis & Vascular, Oncology & Cancer

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5 plate size
50 plate size
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