R-PLEX Human PD1 Antibody Set

R-PLEX Human PD1 Antibody Set Overview
The R-PLEX Human PD1 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of PD1 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human PD1 Antibody Set Features
  • Measures human PD1 in serum, plasma, and cell lysate
  • Dynamic range: 4.6-20,000 pg/mL
  • Median LLOD: 4.6 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human PD1 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human PD1 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human PD1 Antibody Set
PD1 Analyte

Description - Programmed cell death 1 (PD1, CD279, SLEB2, PD-1) is an immune checkpoint receptor that is important in regulating the immune system and its recognition of self. PD1 is expressed by both T cells and B cells. The soluble form of PD1 lacks the transmembrane domain and is a product of splice variants of the PD1 gene. PD1 binds to PD-L1 and PD-L2, which improves anti-tumor immune activity. Plasma concentrations of PD1 (soluble) correlate well with rheumatoid arthritis.

Disease Research Area - Oncology

Application Area - Immunology/Inflammation, Clinical Immunology, Immuno-Oncology

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5 plate size
50 plate size
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