R-PLEX Human PD-L1 Antibody Set

R-PLEX Human PD-L1 Antibody Set Overview
The R-PLEX Human PD-L1 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of PD-L1 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human PD-L1 Antibody Set Features
  • Measures human PD-L1 in plasma, serum, and cell lysate
  • Dynamic range: 0.24-2,000 pg/mL
  • Median LLOD: 0.24 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human PD-L1 Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Human PD-L1 Antibody Set Calibration Curve
R-PLEX Human PD-L1 Antibody Set Calibration Curve
PD-L1 Analyte

Description - Programmed cell death ligand 1 (PD-L1, PDCD1LG1, CD274, B7-H1) is an immune inhibitory ligand that is expressed by T cells, B cells, and various types of tumor cells. Interactions of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation

Disease Research Area - Oncology

Application Area - Oncology & Cancer, Immunology/Inflammation

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Order Details
Catalog No
Size
Price in USD
Qty
F214C-3
5 plate size
$675.00
F214C-8
50 plate size
$6,075.00
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