R-PLEX Human P-Selectin Antibody Set Overview
The R-PLEX Human P-Selectin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of P-Selectin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
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R-PLEX Human P-Selectin Antibody Set Features
- Measures human P-Selectin in serum, plasma, and urine
- Dynamic range: 11 - 200,000 pg/mL
- Median LLOD: 11 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data
Calibration curve for the R-PLEX Human P-Selectin Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Human P-Selectin Antibody Set Calibration Curve
P-Selectin Analyte
Description - P-Selectin (CD62, GRMP, PSEL, CD62P, GMP140, LECAM3, PADGEM, SELP) is a member of the Selectin family of cell surface glycoproteins expressed in granules of endothelial cells and activated platelets. P-selectin plays a critical role in the recruitment of leukocytes to the site of injury during inflammation and is involved in cancer metastasis.
Disease Research Area - Cancer, Inflammation
Application Area - Cell Adhesion, Cardiovascular
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Recommended Components
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Specifications
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Kit Contents
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References
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Documentation
Why do I need other components
Catalog No.
Product Name
Size
R55BB-5
R50AA-4
R92TG-3
L45SA-1
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Application(s)
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Immunology/Inflammation
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Oncology & Cancer
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Analyte(s)
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P-Selectin
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Species
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Human
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Mouse Monoclonal
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Dynamic Range
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11 - 200,000 pg/mL
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Sample Type
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Serum, Plasma, Urine
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Recombinant standards
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Recombinant protein expressed in mouse myeloma cell line, NS0
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LLOD (Sensitivity)
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11 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID(s)
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6403
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UniProt ID(s)
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P16109
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Assay Diluent(s)
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Diluent 10
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Antibody Diluent(s)
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Diluent 3
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Product Description
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Storage
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Quantity per Kit
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Human P-Selectin Antibody Set (5 Plate Size)
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2-8°C
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1 ea
(5 plate size)
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Human P-Selectin Calibrator
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≤-70°C
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5 vial
(1 vial)
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Product Description
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Storage
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Quantity per Kit
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Human P-Selectin Antibody Set (5 Plate Size)
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2-8°C
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10 ea
(5 plate size)
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Human P-Selectin Calibrator
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≤-70°C
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50 vial
(1 vial)
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Title
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Journal
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Year
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Genetic Variants in Platelet Factor 4 Modulate Inflammatory and Platelet Activation Biomarkers.
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Cluster Analysis of Placental Inflammatory Proteins Can Distinguish Preeclampsia from Preterm Labor and Premature Membrane Rupture in Singleton Deliveries Less Than 28 Weeks of Gestation.
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Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV.
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Short-term walnut consumption increases circulating total adiponectin and apolipoprotein A concentrations, but does not affect markers of inflammation or vascular injury in obese humans with the metabolic syndrome: data from a double-blinded, randomized, placebo-controlled study.
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Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease.
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Product Inserts
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Product Highlights
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SDS
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Handouts
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Datasheets
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Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
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