R-PLEX Human P-Selectin Antibody Set Overview
The R-PLEX Human P-Selectin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of P-Selectin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
click here.
R-PLEX Human P-Selectin Antibody Set Features
- Measures human P-Selectin in serum, plasma, and urine
- Dynamic range: 11 - 200,000 pg/mL
- Median LLOD: 11 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data
Calibration curve for the R-PLEX Human P-Selectin Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Human P-Selectin Antibody Set Calibration Curve
P-Selectin Analyte
Description - P-Selectin (CD62, GRMP, PSEL, CD62P, GMP140, LECAM3, PADGEM, SELP) is a member of the Selectin family of cell surface glycoproteins expressed in granules of endothelial cells and activated platelets. P-selectin plays a critical role in the recruitment of leukocytes to the site of injury during inflammation and is involved in cancer metastasis.
Disease Research Area - Cancer, Inflammation
Application Area - Cell Adhesion, Cardiovascular
-
Recommended Components
-
Specifications
-
Kit Contents
-
References
-
Resources
You will need plates, diluents, and read buffer to run your assay.
Please select from the below menu.
Catalog No.
Product Name
Size
L45SA-1
R55BB-5
R50AA-4
R92TG-3
|
Application(s)
|
|
Immunology/Inflammation
,
Oncology & Cancer
|
|
Analyte(s)
|
|
P-Selectin
|
|
Species
|
|
Human
|
|
Capture Antibody
|
|
Mouse Monoclonal
|
|
Detection Antibody
|
|
Mouse Monoclonal
|
|
Dynamic Range
|
|
11 - 200,000 pg/mL
|
|
Sample Type
|
|
Serum, Plasma, Urine
|
|
Recombinant standards
|
|
Recombinant protein expressed in mouse myeloma cell line, NS0
|
|
LLOD (Sensitivity)
|
|
11 pg/mL
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
Storage Statement
|
|
Please refer to the product insert for the storage conditions of individual kit components.
|
|
Storage Condition
|
|
Multi-Component
|
|
Gene ID
|
|
6403
|
|
UniProt ID
|
|
P16109
|
|
Assay Diluent(s)
|
|
Diluent 10
|
|
Antibody Diluent(s)
|
|
Diluent 3
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
Human P-Selectin Antibody Set (5 Plate Size)
|
2-8°C | 1 ea
(5 plate size) |
|
Human P-Selectin Calibrator
|
≤-70°C | 5 vial
(1 vial) |
|
Product Description
|
Storage
|
Quantity per Kit
|
|
Human P-Selectin Antibody Set (5 Plate Size)
|
2-8°C | 10 ea
(5 plate size) |
|
Human P-Selectin Calibrator
|
≤-70°C | 50 vial
(1 vial) |
|
Title
|
Journal
|
Year
|
|
Genetic Variants in Platelet Factor 4 Modulate Inflammatory and Platelet Activation Biomarkers.
|
|
|
|
Cluster Analysis of Placental Inflammatory Proteins Can Distinguish Preeclampsia from Preterm Labor and Premature Membrane Rupture in Singleton Deliveries Less Than 28 Weeks of Gestation.
|
|
|
|
Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV.
|
|
|
|
Short-term walnut consumption increases circulating total adiponectin and apolipoprotein A concentrations, but does not affect markers of inflammation or vascular injury in obese humans with the metabolic syndrome: data from a double-blinded, randomized, placebo-controlled study.
|
|
|
|
Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease.
|
|
|
|
|
|
|
Product Inserts
|
|
|
|
Product Highlights
|
|
|
|
SDS
|
|
|
|
Handouts
|
|
|
|
Datasheets
|
|
|
Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters