R-PLEX Human P-Selectin Antibody Set Overview
The R-PLEX Human P-Selectin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of P-Selectin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
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R-PLEX Human P-Selectin Antibody Set Features
- Measures human P-Selectin in serum, plasma, and urine
- Dynamic range: 11 - 200,000 pg/mL
- Median LLOD: 11 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data
Calibration curve for the R-PLEX Human P-Selectin Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Human P-Selectin Antibody Set Calibration Curve
P-Selectin Analyte
Description - P-Selectin (CD62, GRMP, PSEL, CD62P, GMP140, LECAM3, PADGEM, SELP) is a member of the Selectin family of cell surface glycoproteins expressed in granules of endothelial cells and activated platelets. P-selectin plays a critical role in the recruitment of leukocytes to the site of injury during inflammation and is involved in cancer metastasis.
Disease Research Area - Cancer, Inflammation
Application Area - Cell Adhesion, Cardiovascular
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Recommended Components
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Specifications
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Kit Contents
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References
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Documentation
You will need plates, diluents, and read buffer to run your assay. Please select from the below menu.
R-PLEX Sets are intended to be used with other MSD components such as plates, diluents and MSD Read Buffer. If you don’t already have these items, you can purchase them along with your Antibody Set(s). The “Recommended Components” tab provides helpful suggestions or you can call MSD Customer Service (Phone number) for assistance. R-PLEX Sets can also be used with other antibody sets such as U-PLEX antibody sets (make a link to UPLEX landing page) for multiplex measurements.
Catalog No.
Product Name
Size
R55BB-5
R50AA-4
R92TG-3
L45SA-1
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Application(s)
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Immunology/Inflammation
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Oncology & Cancer
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Analyte(s)
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P-Selectin
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Species
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Human
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Mouse Monoclonal
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Dynamic Range
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11 - 200,000 pg/mL
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Sample Type
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Serum, Plasma, Urine
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Recombinant standards
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Recombinant protein expressed in mouse myeloma cell line, NS0
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LLOD (Sensitivity)
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11 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID(s)
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6403
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UniProt ID(s)
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P16109
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Assay Diluent(s)
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Diluent 10
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Antibody Diluent(s)
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Diluent 3
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Product Description
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Storage
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Quantity per Kit
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Human P-Selectin Antibody Set (5 Plate Size)
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2-8°C
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1 ea
(5 plate size)
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Human P-Selectin Calibrator
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≤-70°C
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5 vial
(1 vial)
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Product Description
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Storage
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Quantity per Kit
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Human P-Selectin Antibody Set (5 Plate Size)
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2-8°C
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10 ea
(5 plate size)
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Human P-Selectin Calibrator
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≤-70°C
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50 vial
(1 vial)
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Title
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Journal
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Year
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Genetic Variants in Platelet Factor 4 Modulate Inflammatory and Platelet Activation Biomarkers.
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Cluster Analysis of Placental Inflammatory Proteins Can Distinguish Preeclampsia from Preterm Labor and Premature Membrane Rupture in Singleton Deliveries Less Than 28 Weeks of Gestation.
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Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV.
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Short-term walnut consumption increases circulating total adiponectin and apolipoprotein A concentrations, but does not affect markers of inflammation or vascular injury in obese humans with the metabolic syndrome: data from a double-blinded, randomized, placebo-controlled study.
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Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease.
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Product Inserts
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Product Highlights
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SDS
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Handouts
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Datasheets
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Order Details
Catalog No
Size
Price in USD
Qty
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Scientific/Technical Support
Instrument Support
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