R-PLEX Human OX40 Antibody Set

R-PLEX Human OX40 Antibody Set Overview
The R-PLEX Human OX40 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of OX40 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human OX40 Antibody Set Features
  • Measures human OX40 in serum, plasma, and cell lysate
  • Dynamic range: 2.0-25,000 pg/mL
  • Median LLOD: 2.0 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human OX40 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human OX40 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human OX40 Antibody Set
OX40 Analyte

Description - OX40 (TNFRSF4, ACT35, CD134, OX40 receptor) is an immune checkpoint receptor that is expressed by T cells including cytotoxic T cells and regulatory T cells (Treg). Binding of the OX40 ligand (OX40L) to the OX40 receptor on cytotoxic T cells promotes replication and survival. When OX40L binds to OX40 on Tregs, their suppression of cytotoxic T cells is muted, resulting in enhanced T-cell activation.

Disease Research Area - Autoimmune & Inflammation

Application Area - Immunology/Inflammation, Immuno-Oncology

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5 plate size
50 plate size
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