R-PLEX Human OX40 Antibody Set Overview
The R-PLEX Human OX40 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of OX40 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
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R-PLEX Human OX40 Antibody Set Features
- Measures human OX40 in serum, plasma, and cell lysate
- Dynamic range: 2.0-25,000 pg/mL
- Median LLOD: 2.0 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data
Calibration curve for the R-PLEX Human OX40 Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Human OX40 Antibody Set Calibration Curve
OX40 Analyte
Description - OX40 (TNFRSF4, ACT35, CD134, OX40 receptor) is an immune checkpoint receptor that is expressed by T cells including cytotoxic T cells and regulatory T cells (Treg). Binding of the OX40 ligand (OX40L) to the OX40 receptor on cytotoxic T cells promotes replication and survival. When OX40L binds to OX40 on Tregs, their suppression of cytotoxic T cells is muted, resulting in enhanced T-cell activation.
Disease Research Area - Autoimmune & Inflammation
Application Area - Immunology/Inflammation, Immuno-Oncology
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Recommended Components
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Specifications
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Kit Contents
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Documentation
You will need plates, diluents, and read buffer to run your assay. Please select from the below menu.
R-PLEX Sets are intended to be used with other MSD components such as plates, diluents and MSD Read Buffer. If you don’t already have these items, you can purchase them along with your Antibody Set(s). The “Recommended Components” tab provides helpful suggestions or you can call MSD Customer Service (Phone number) for assistance. R-PLEX Sets can also be used with other antibody sets such as U-PLEX antibody sets (make a link to UPLEX landing page) for multiplex measurements.
Catalog No.
Product Name
Size
R50AA-4
R92TG-3
L45SA-1
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Application(s)
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Immunology/Inflammation
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Immunogenicity
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Analyte(s)
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OX40
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Species
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Human
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Goat Polyclonal
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Dynamic Range
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2.0-25,000 pg/mL
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Sample Type
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Serum, Plasma, Cell Lysate
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LLOD (Sensitivity)
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2.0 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID(s)
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7293
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UniProt ID(s)
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P43489
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Assay Diluent(s)
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Diluent 12
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Antibody Diluent(s)
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Diluent 12
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Product Description
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Storage
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Quantity per Kit
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Human OX40 Antibody Set (5 Plate Size)
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2-8°C
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1 ea
(5 plate size)
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Human OX40 Calibrator
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≤-70°C
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5 vial
(1 vial)
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Product Description
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Storage
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Quantity per Kit
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Human OX40 Antibody Set (5 Plate Size)
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2-8°C
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10 ea
(5 plate size)
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Human OX40 Calibrator
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≤-70°C
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50 vial
(1 vial)
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Product Inserts
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SDS
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Handouts
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Datasheets
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Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters