R-PLEX Human OX40 Antibody Set Overview
The R-PLEX Human OX40 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of OX40 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
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R-PLEX Human OX40 Antibody Set Features
- Measures human OX40 in serum, plasma, and cell lysate
- Dynamic range: 2.0-25,000 pg/mL
- Median LLOD: 2.0 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data
Calibration curve for the R-PLEX Human OX40 Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Human OX40 Antibody Set Calibration Curve
OX40 Analyte
Description - OX40 (TNFRSF4, ACT35, CD134, OX40 receptor) is an immune checkpoint receptor that is expressed by T cells including cytotoxic T cells and regulatory T cells (Treg). Binding of the OX40 ligand (OX40L) to the OX40 receptor on cytotoxic T cells promotes replication and survival. When OX40L binds to OX40 on Tregs, their suppression of cytotoxic T cells is muted, resulting in enhanced T-cell activation.
Disease Research Area - Autoimmune & Inflammation
Application Area - Immunology/Inflammation, Immuno-Oncology
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Recommended Components
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Specifications
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Kit Contents
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Documentation
Why do I need other components
Catalog No.
Product Name
Size
R50AA-4
R92TG-3
L45SA-1
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Application(s)
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Immunology/Inflammation
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Immunogenicity
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Analyte(s)
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OX40
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Species
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Human
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Goat Polyclonal
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Dynamic Range
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2.0-25,000 pg/mL
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Sample Type
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Serum, Plasma, Cell Lysate
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LLOD (Sensitivity)
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2.0 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID(s)
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7293
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UniProt ID(s)
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P43489
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Assay Diluent(s)
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Diluent 12
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Antibody Diluent(s)
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Diluent 12
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Product Description
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Storage
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Quantity per Kit
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Human OX40 Antibody Set (5 Plate Size)
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2-8°C
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1 ea
(5 plate size)
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Human OX40 Calibrator
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≤-70°C
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5 vial
(1 vial)
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Product Description
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Storage
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Quantity per Kit
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Human OX40 Antibody Set (5 Plate Size)
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2-8°C
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10 ea
(5 plate size)
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Human OX40 Calibrator
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≤-70°C
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50 vial
(1 vial)
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Product Inserts
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SDS
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Handouts
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Datasheets
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Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters