R-PLEX Human MMP-9 Total Antibody Set

R-PLEX Human MMP-9 (total) Antibody Set Overview
The R-PLEX Human MMP-9 (total) Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of MMP-9 (total) in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human MMP-9 (total) Antibody Set Features
  • Measures human MMP-9 (total) in serum, plasma
  • Dynamic range: 1.35 - 100,000 pg/mL
  • Median LLOD: 1.35 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human MMP-9 (total) Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Human MMP-9 (total) Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human MMP-9 (tota) Antibody Set
MMP-9 (total) Analyte

Description - Total Matrix MetalloProteinase 9 (MMP-9, GELB, CLG4B, MANDP2, 92kDa type IV collagenase) is an endoproteinase that is important in extracellular matrix remodeling. MMPs are a highly homologous family of proteins. MMP-9 degrades interstitial proteins and can cleave non-matrix molecules such as IL-1β, IL-8, and platelet factor-4. MMP-9 plays an important role in various diseases including cancer, rheumatoid arthritis and atherosclerosis. MMP-9 is secreted as an inactive proenzyme (proMMP-9), which is activated by MMP-3. Total MMP-9 includes both proMMP-9 and active MMP-9.

Disease Research Area - Autoimmune & Inflammation, Oncology

Application Area - Oncology & Cancer, Immunology/Inflammation

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Order Details
Catalog No
Size
Price in USD
Qty
F215Q-3
5 plate size
$550.00
F215Q-8
50 plate size
$4,950.00
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