R-PLEX Human LAG3 Antibody Set

R-PLEX Human LAG3 Antibody Set Overview
The R-PLEX Human LAG3 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of LAG3 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human LAG3 Antibody Set Features
  • Measures human LAG3 in serum, plasma, and cell lysate
  • Dynamic range: 7.3-60,000 pg/mL
  • Median LLOD: 7.3 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human LAG3 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human LAG3 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human LAG3 Antibody Set
LAG3 Analyte

Description - Lymphocyte-Activation Gene 3 (LAG3, CD223, LAG-3, FDC) encodes the LAG3 protein that is a member of the immunoglobulin superfamily. It is expressed on activated T cells, NK cells, B cells, and plasmacytoid dendritic cells, and binds with high affinity to MHC class II molecules. LAG3 is an immune checkpoint receptor that is of interest in immunotherapy and certain autoimmune disorders. LAG3 antagonists activate T effector cells and inhibit regulatory T-cell suppression.

Disease Research Area - Oncology

Application Area - Oncology & Cancer, Immunology/Inflammation, Immuno-Oncology

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Order Details
Catalog No
Size
Price in USD
Qty
F213Y-3
5 plate size
$800.00
F213Y-8
50 plate size
$7,200.00
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