R-PLEX Human Granzyme B Antibody Set

R-PLEX Human Granzyme B Antibody Set Overview
The R-PLEX Human Granzyme B Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Granzyme B in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human Granzyme B Antibody Set Features
  • Measures human Granzyme B in serum, plasma, and cell lysate
  • Dynamic range: 0.30-2,000 pg/mL
  • Median LLOD: 0.30 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human Granzyme B Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human Granzyme B Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human Granzyme B Antibody Set
Granzyme B Analyte

Description - Granzyme B (GZMB, C11, CTLA-1, CTSGL1, SECT) is a protease found in secretory granules of cytotoxic T cells and NK cells. When secreted into the target cell, Granzyme B causes cell death by activating many of the caspase enzymes present inside cells. Granzyme B has other functions including stimulating the release of proinflammatory cytokines and remodeling of extracellular matrices. It may also play a role in the development of chronic obstructive pulmonary disease and hair loss.

Disease Research Area - Infectious Diseases

Application Area - Immunology/Inflammation, Immuno-Oncology

  • Recommended Components
  • Specifications
  • Kit Contents
  • References
  • Documentation
Order Details
Catalog No
Price in USD
5 plate size
50 plate size
Customer Service/Orders

Scientific/Technical Support

Instrument Support

Company Headquarters